Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis |
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| Authors: | Zhao Jian Dong Li Lu Bin Wu Guobin Xu Dongmei Chen Jingjing Li Kai Tong Xin Dai Jianxin Yao Side Wu Mengchao Guo Yajun |
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| Affiliation: | International Cancer Institute and Eastern Hospital of Hepatobiliary Surgery, Second Military Medical University, Shanghai, People's Republic of China. |
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| Abstract: | |
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| Keywords: | 5-FU, 5-fluorouracil GFP, green fluorescent protein MMP, mitochondrial membrane potential NF-κB, nuclear factor-κB OPN, osteopontin shNon, nonsilencing shRNA shOPN, shRNA targeting OPN shRNA, short-hairpin RNA TMRE, tetramethylrhodamine ethylester TUNEL, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling |
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