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Transient receptor potential vanilloid-4 has a major role in visceral hypersensitivity symptoms
Authors:Cenac Nicolas  Altier Christophe  Chapman Kevin  Liedtke Wolfgang  Zamponi Gerald  Vergnolle Nathalie
Affiliation:Department of Pharmacology and Therapeutics, University of Calgary, Calgary, Alberta, Canada.
Abstract:
Keywords:4α-PDD, 4 α-phorbol 12,13-didecanoate   6-FAM, 6-carboxyfluorescein   CRD, colorectal distension   DRG, dorsal root ganglia   IBS, irritable bowel syndrome   mRNA, messenger RNA   PAR2, protease-activated receptor 2   siRNA, small interfering RNA   TRP, transient receptor potential   TRPV4, transient receptor potential vanilloid 4   VMR, visceral motor response
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