Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study |
| |
| Authors: | Justus HW Jansen Olav P van der Jagt Bas J Punt Jan AN Verhaar Johannes PTM van Leeuwen Harrie Weinans Holger Jahr |
| |
| Affiliation: | (1) Department of Orthopaedics, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands;(2) Department of Internal Medicine, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands;(3) Department of Surgery, Albert Schweitzer Hospital, P.O. Box 444, 3300 AK Dordrecht, The Netherlands |
| |
| Abstract: | Background Although pulsed electromagnetic field (PEMF) stimulation may be clinically beneficial during fracture healing and for a wide range of bone disorders, there is still debate on its working mechanism. Mesenchymal stem cells are likely mediators facilitating the observed clinical effects of PEMF. Here, we performed in vitro experiments to investigate the effect of PEMF stimulation on human bone marrow-derived stromal cell (BMSC) metabolism and, specifically, whether PEMF can stimulate their osteogenic differentiation. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
