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人参皂苷生物转化研究进展
引用本文:郭从亮,崔秀明,杨晓艳,武双. 人参皂苷生物转化研究进展[J]. 中国中药杂志, 2014, 39(20): 3899-3904
作者姓名:郭从亮  崔秀明  杨晓艳  武双
作者单位:昆明理工大学 生命科学与技术学院, 云南 昆明 650500;中药质量与资源开发滇澳联合实验室, 云南 昆明 650500;昆明理工大学 生命科学与技术学院, 云南 昆明 650500;中药质量与资源开发滇澳联合实验室, 云南 昆明 650500;昆明理工大学 生命科学与技术学院, 云南 昆明 650500;中药质量与资源开发滇澳联合实验室, 云南 昆明 650500;昆明理工大学 生命科学与技术学院, 云南 昆明 650500;中药质量与资源开发滇澳联合实验室, 云南 昆明 650500
基金项目:昆明理工大学自然研究基金项目(KKSY201426015);云南省教育厅科学研究基金重点项目(2014Z029)
摘    要:人参皂苷是人参属植物药理活性的重要物质,尤以稀有人参皂苷及苷元的抗肿瘤,保护神经系统,保肝护肝等药理活性最为显著,因此,研究稀有人参皂苷获取的方法也日益增多。该文对人参属植物中人参皂苷的生物转化进行了简要的概述和展望。

关 键 词:人参属  皂苷类  生物转化  稀有人参皂苷  β-葡萄糖苷酶
收稿时间:2014-04-28

Advances in studies on biotransformation of ginsensides
GUO Cong-liang,CUI Xiu-ming,YANG Xiao-yan and WU Shuang. Advances in studies on biotransformation of ginsensides[J]. China Journal of Chinese Materia Medica, 2014, 39(20): 3899-3904
Authors:GUO Cong-liang  CUI Xiu-ming  YANG Xiao-yan  WU Shuang
Affiliation:Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Kunming 650500, China;Yunnan and Macau Joint Laboratory of Traditional Chinese Medicine Quality and Resources Development, Kunming 650500, China;Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Kunming 650500, China;Yunnan and Macau Joint Laboratory of Traditional Chinese Medicine Quality and Resources Development, Kunming 650500, China;Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Kunming 650500, China;Yunnan and Macau Joint Laboratory of Traditional Chinese Medicine Quality and Resources Development, Kunming 650500, China;Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Kunming 650500, China;Yunnan and Macau Joint Laboratory of Traditional Chinese Medicine Quality and Resources Development, Kunming 650500, China
Abstract:Ginseng saponins are a type of important active substances in the ginseng genus plants. They have notable pharmacological activities of antineoplastic, neuroprotective, and hepatoprotective activities, which have been drawn more attention to obtain minor ginsenosides by all kinds of methods. In this review, we discussed the latest progress for enrichment of minor ginsenosides by biological transformation of major ginsenosides. At the same time, we have a brief outlook of the research at bioconversion of ginseng saponins.
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