剖宫产围手术期预防使用抗菌药物分析

目的：探讨剖宫产围手术期用药情况，观察分析抗菌药物整治活动前后应用抗菌药物的变化。方法：对2010-2012年1569例妇产科剖宫产手术患者进行调查，用SPSS 13．0统计软件对剖宫产围手术期用药、用药种类、联合用药、药品费用等资料进行统计分析。结果：1569例剖宫产患者抗菌药物应用率100%；其中抗菌药物整治活动前使用率排名前三位的是阿奇霉素、头孢硫脒和奥硝唑，抗菌药物整治活动后排名前三位的是头孢硫脒、头孢呋辛、克林霉素，选择药物趋于合理化，两组切口感染率无显著性差异。联合用药比例降低。药品费用分析提示抗菌药物整治活动对药费影响具有统计学意义。结论：医院剖宫产围手术期抗菌药物整治活动有助于合理用药，并降低抗菌药物使用费用。

Analysis on the use of antibacterial drugs during preoperative period of cesarean sections

Objective: To investigate the use of antibacterial drugs during the perioperative period of a cesarean section and observe the differences before and after antibacterial drug remediation. Methods: 1 569 cesarean cases from 2010 to 2012 were investigated, and the use of antibacterial drugs, drug categories, drug combinations, medical expenses, and so on was statistically analyzed with the use of the statistical software SPSS13.0. Results: The rate of antibacterial drug usage within the 1 569 cesarean cases was 100%; for pre-operative antibacterial drug remediation, azithromycin, cefathiamidine, and ornidazole were the top three, while the top three antibacterial drugs for post-operative remediation were arecefathiamidine, cefuroxime, and clindamycin. There was no significant difference between the two groups of incision infections, and the rate for combined use of drugs dropped. The analysis of drug costs is of statistical significance. Conclusion: The analysis of antibacterial drug remediation is useful for the rational use of antibacterial drugs and a reduction of costs.