| 白血病患者血清IL-8的测定 |
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| 引用本文： | 李庆山,温春光,洪文德,许多荣.白血病患者血清IL-8的测定[J].新医学,2000,31(1):21-22. |
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| 作者姓名： | 李庆山 温春光 洪文德 许多荣 |
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| 作者单位： | 1. 广州市第一人民医院血液科,510180
2. 中山医科大学附属第一医院血液科,510080 |
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| 摘 要： | 目的：探讨血清白细胞介素８（ＩＬ－８）变化在白血病中的意义。方法：采用平似酶联免疫吸附法测定了１０例急性淋巴细胞白血病（ＡＬＬ），２５例急性非淋巴细胞白血病（ＡＮＬＬ），１１例慢性粒细胞白血病（ＣＭＬ）慢性期血清ＩＬ－８浓度。结果：ＡＬＬ、ＡＮＬＬ和ＣＭＬ患者血清ＩＬ－８水平显著高于正常对照组，ＡＬＬ与ＡＮＬＬ患者无显著性差异，急性单细胞白血病组水平显著高于急粒白细胞病（Ｍ１￣Ｍ３）组，治疗有铲的
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| 关 键 词： | 白细胞介素8 白血病 淋巴细胞 非淋巴细胞 |
Determination of serum interleukin-8 in leukemia patients |
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| Li Qingshan,Wen Chunguang,Hong Wende,et al.Determination of serum interleukin-8 in leukemia patients[J].New Chinese Medicine,2000,31(1):21-22. |
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| Authors: | Li Qingshan Wen Chunguang Hong Wende |
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| Institution: | Li Qingshan,Wen Chunguang,Hong Wende,et al Department of Hematology,First Municipal Hospital,Guangzhou,510180 |
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| Abstract: | Objective:To study the clinical value significance of serum interleukin-8 (IL-8) in leukemia patients. Methods:Serum interleukin-8 levels were measured in 10 patients with acute lymphocytic leukemia(ALL), 25 with acute non- lym-phocytic leukemia(ANLL)and 11 with chronic myelogenous leukemia(CML)at chronic phase by sandwich enzyme linked immnosorbent assay (ELISA ). Results: Significantly higher IL- 8 were found in ALL, ANLL and CML patients compared to normal controls(p <0.01 ). There were no significant differences in IL-8 level between ALL and ANLL patients(p >0.05).Serum IL-8 levels in M5 patients was significantly higher than that of ANLL patients. IL-8 levels significantly declined after effective treatment in CML patients. Conclusion: Serum IL- 8 level may be helpful in typing of ANLL and in monitoring CML response to treatment. |
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| Keywords: | Interleukin-8 Leukemia Lymphocyes Non--lymphocyes Myelogenous chronic Enzymelnked immnosorbent assay |
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