椎间盘组织工程学髓核种子细胞的研究新进展

椎间盘退行性变是临床的常见病,其病因尚不明确,可引起的一系列疾病如腰椎间盘突出症、颈椎病、椎间盘源性疼痛、椎管狭窄症以及脊柱节段不稳等,是导致腰腿痛和影响患者生活质量的常见原因之一。目前临床上的各种治疗办法或多或少存在着许多难以克服的问题,随着椎间盘髓核细胞组织工程学研究的不断深入,为椎间盘退行性变的治疗带来了新的希望,但其种子细胞的来源和鉴定等方面仍有许多问题亟待解决。

Progress in the study on intervertebral disc tissue engineering nucleus pulposus seed cells

Intervertebral disc degeneration is a common and agnogenic clinical disease.It can lead to a series of symptom,such as protrusion of lumbar intervertebral disc,cervical spondylosis,discogenic pain,spinal stenosis and spinal segmental instability.It can result in the lumbocrural pain and greatly lower the patients' living quality.At present there are still some difficulties in the clinical treatments to be overcome.With the development of the nucleus tissue engineering,appears the new treatment for intervertebral disc degeneration,but the problem of the source and identification of seed cells still need to be solved.