非肌层浸润性膀胱癌的治疗现状

膀胱癌是泌尿系统最常见的恶性肿瘤之一,是一种直接威胁患者生存的疾病。非肌层浸润性膀胱癌(non-muscle invasive bladder cancer,NMIBC)占初发膀胱肿瘤的70%,包括Ta,T1和Tis。经尿道膀胱肿瘤电切术和术后膀胱内灌注化疗是目前NMIBC主要的治疗方式。虽经治疗,仍有相当一部分患者出现复发和进展。近年来,一些新的治疗手段和灌注方法不断应用于临床,为NMIBC的治疗开辟了新的思路。本文对非肌层浸润性膀胱癌的治疗现状进行综述,以期对临床防治膀胱肿瘤提供指导。

Current treatment of non-muscle-invasive bladder cancer

Bladder cancer is one of the most common malignant tumors of the urinary system.It is a disease that threats the patients' survival.Non-muscle-invasive bladder cancer is accounted for 70% in primary bladder tumors,which include Ta,T1 and Tis.Transurethral resection of bladder tumor(TURBT) with postoperative instillation of chemotherapy is the main treatment for NMIBC.Although after treatment,there are a considerable proportion of patients occur recurrence and progression.In recent years,some new treatments and instillation methods have been applied to clinical treatment,which provide some new ideas for the methods of NMIBC.This review focuses on the current treatment of non-muscle invasive bladder cancer,which will provide a new guidance for clinical treatment.