散瘀止痛巴布膏对大鼠试验性炎症和疼痛药效学研究

目的研究散瘀止痛巴布膏对大鼠试验模型的抗炎和镇痛作用。方法通过对二甲苯致小鼠耳肿胀和角叉菜引起的大鼠足趾肿胀的作用观察抗炎作用;通过对醋酸引起的扭体反应的影响及热板法观察镇痛作用。结果散瘀止痛巴布膏对角叉菜胶致大鼠足肿胀和二甲苯致耳肿胀有显著的抑制作用;能明显抑制由醋酸引起的小鼠扭体次数,显著提高小鼠的痛阈值。结论散瘀止痛巴布膏具有显著的消肿抗炎、镇痛作用。

The pharmacodynamic study of the Ba Bu dissipation blood clot and pain-relieving cream on experimental inflammation symptom and ache of rat

Objective To explore the roles of Ba Bu cream in the anti-inflammation and pain relief of rat.Methods The anti-inflammation roles of the Ba Bu cream were evaluated by observation of effects on mouse ear swell induced by xylene and rat toe swell caused by cape fork vegetable.The effects of pain relief were evaluated by observation of the twist of the body reaction caused by acetic acid and the hot plank method.Results The Ba Bu cream has significant effects on the rat toe and ear swell caused by xylene and cape fork vegetable.It can decrease twist number cause by the acetic acid and significantly increase the pain threshold.Conclusion The Ba Bu cream has the significant effects on pain-relieving,swell-decreasing and anti-inflammation.