| 多西紫杉醇联合奥沙利铂和氟尿嘧啶治疗晚期胃癌21例 |
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| 引用本文： | 江汉龙,颜艳,金峰.多西紫杉醇联合奥沙利铂和氟尿嘧啶治疗晚期胃癌21例[J].中国实用医药,2010,5(4):34-36. |
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| 作者姓名： | 江汉龙 颜艳 金峰 |
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| 作者单位： | 南京军区福州总医院476临床部消化肿瘤科,350002 |
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| 摘 要： | 目的观察多西紫杉醇联合奥沙利铂和氟尿嘧啶治疗晚期胃癌的疗效和毒副反应。方法21例晚期胃癌患者采用多西紫杉醇联合奥沙利铂和氟尿嘧啶方案治疗,评价近期疗效和毒副反应,疾病进展时间（TTP）和中位生存期（MST）。结果21例均可评价疗效,其中完全缓解1例,部分缓解11例,稳定5例,进展4例。有效率为57.14%,中位TTP为5.8个月,MST为10.5个月。毒副反应主要是骨髓抑制,其次为胃肠道反应、口腔黏膜炎、腹泻及周围神经毒性。结论多西紫杉醇联合奥沙利铂和氟尿嘧啶方案治疗晚期胃癌的疗效较好,毒副反应可以耐受。
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| 关 键 词： | 奥沙利铂 多西紫杉醇 氟尿嘧啶 晚期胃癌 化学治疗 |
21 cases of advanced gastric cancer treated with docetaxel combined with oxaliplatin and fluorouracil |
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| JIANG Han-long,YAN Yan,JIN Feng.21 cases of advanced gastric cancer treated with docetaxel combined with oxaliplatin and fluorouracil[J].China Practical Medical,2010,5(4):34-36. |
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| Authors: | JIANG Han-long YAN Yan JIN Feng |
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| Institution: | JIANG Han-long,YAN Yan,JIN Feng .Department of Digesgestive Oncology,476 Clinical Department,Fuzhou General Hospital of Nanjing Military Comm,,Fuzhou 350002,China |
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| Abstract: | Objective To evaluate the efficacy and adverse effects of docetaxel combined with oxaliplatin and fluorouracil in treating patients with advanced gastrice cancer.Methods 21 cases of advanced gastric cancer patients have been treated with the formula of docetaxel combined with oxaliplatin and fluorouracil.The near-term efficacy and adverse effects were evaluated.time to progression (TTP)and median survival time(MST) have been observed at the same time.Results Among 21 cases,1 achieved complete response,11 pa... |
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| Keywords: | Docetaxel Oxaliplatin Fluorouracil Advanced gastric cancer Chemotherapy |
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