| 肝血管平滑肌脂肪瘤7例临床病理观察 |
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| 引用本文： | 张宏图,孙耘田,邹霜梅,刘秀云,沈桂华,郭蕾.肝血管平滑肌脂肪瘤7例临床病理观察[J].诊断病理学杂志,2002,9(2):85-87. |
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| 作者姓名： | 张宏图 孙耘田 邹霜梅 刘秀云 沈桂华 郭蕾 |
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| 作者单位： | 中国医学科学院,中国协和医科大学,肿瘤医院病理科,北京,100021 |
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| 摘 要： | 目的 探讨肝血管平滑肌脂肪瘤的病理形态、免疫组化及诊断和鉴别诊断要点。方法 对7例肝血管平滑肌脂肪瘤病例进行临床病理与免疫组织化学观察。结果 7例肝血管平滑肌脂肪瘤男:女＝3：4，平均43岁，肿瘤大小4．6－23cm，平均10cm 。4例混合型，2例梭形细胞型，1例上皮样型。7例均HMB－45（＋），3例desmin( )，5例actin( )。结论 肝血管平滑肌脂肪瘤的3种成分分布、比例及病理形态变化多样，并易见髓外造血，HMB－45阳性细胞是诊断肝血管平滑肌脂肪瘤的重要指标之一。
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| 关 键 词： | 肝血管平滑肌脂肪瘤 免疫组化 HMB－45 病理 |
| 文章编号： | 1007-8096(2002)02-0085-03 |
| 修稿时间： | 2001年10月11 |
Hepatic angiomyolipoma: a clinicopathological analysis of 7 cases |
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| Zhang Hongtu,Sun Yuntian,Zou Shuangmei,et al..Hepatic angiomyolipoma: a clinicopathological analysis of 7 cases[J].Chinese Journal of Diagnostic Pathology,2002,9(2):85-87. |
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| Authors: | Zhang Hongtu Sun Yuntian Zou Shuangmei |
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| Institution: | Zhang Hongtu,Sun Yuntian,Zou Shuangmei,et al. Department of Pathology,Cancer Institute and Hospital,the Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100021 |
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| Abstract: | Objective To study the clinicopathologic and immunohistochemical characteristics and differential diagnosis of hepatic angiomyolipoma (HAML). Methods Seven cases of HAML were analyzed using H&E and immunohistochemical stains. Results This group of HAML cases was composed of 4 females and 3 males, with age ranged 25-65 years (median 43 years). The size of the tumors was 4.6 cm to 23 cm (median 10 cm). 4 cases were mixed type, 2 spindle cell type and 1 epithelioid type. Immunohistochemical staining showed that all the cases were positive for HMB 45 and S 100, 5 positive for actin and 2 positive for desmin. Conclusions HAML is composed of a varying mixture of three tissue components. Extramedullary hemopoiesis is often found. HMB 45 positive myoid cell is one of important markers for the diagnosis of HAML. |
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| Keywords: | Angiomyolipoma hepatic Immunohistochemistry HMB 45 |
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