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Identification of cytochrome P450s involved in the metabolism of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1) using human recombinant enzymes and rat liver microsomes in vitro |
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| Authors: | Ying-Yuan Lu Hai-Xu Cheng Xin Wang Xiao-Wei Wang Jun-Yi Liu Pu Li |
| Institution: | 1. Department of Pharmacology, School of Basic Medical Science, Beijing (Peking) University, Beijing, PR China,;2. Department of Chemical Biology, School of Pharmaceutical Sciences, Beijing (Peking) University, Beijing, PR China, |
| Abstract: | |
| Keywords: | Human recombinant cytochrome P450 liquid chromatography-ion trap-time of flight-mass spectrometry (LC-IT-TOF-MS) metabolism in vitro rat liver microsomes 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1) |