| 基于Excel函数设计单室模型间歇静脉滴注给药方案 |
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| 引用本文： | 袁进,石磊,赵树进. 基于Excel函数设计单室模型间歇静脉滴注给药方案[J]. 中国药房, 2007, 18(8): 581-582 |
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| 作者姓名： | 袁进 石磊 赵树进 |
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| 作者单位： | 广州军区广州总医院药剂科,广州市,510010 |
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| 基金项目： | 广东省医院药学研究基金 |
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| 摘 要： | 设计单室模型间歇静脉滴注给药方案。方法:根据药动学参数,用Excel编写程序。结果:输入t1/2、Vd、有效治疗范围等,可计算出给药时间间隔、滴注速度(k0),而且可绘制药-时曲线。结论:该方法适用于任何一种符合单室模型间歇静脉滴注给药特征的药物,可迅速得到所有结果,且简单、可靠、直观。
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| 关 键 词： | Excel 单室模型 间歇静脉滴注 给药方案 设计 |
| 文章编号： | 1001-0408(2007)08-0581-02 |
| 收稿时间： | 2006-09-11 |
| 修稿时间： | 2006-10-26 |
Excel - based Design of One Compartment Model Intermittent Intravenous Drip Dosage Regimen |
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| YUAN Jin,SHI Lei,ZHAO Shujin. Excel - based Design of One Compartment Model Intermittent Intravenous Drip Dosage Regimen[J]. China Pharmacy, 2007, 18(8): 581-582 |
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| Authors: | YUAN Jin SHI Lei ZHAO Shujin |
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| Affiliation: | Dept .of Pharmacy, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China |
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| Abstract: | OBJECTIVE: To design one compartment model intermittent intravenous dosage regimen.METHODS: Programming was performed by means of Excel based on pharmacokinetic parameters.RESULTS: The related data such as administration interval and speed of drip could be figured out and the time-concentration curves could be drawn if the data including half-time(t1/2),apparent volume of distribution(Vd) and effective therapeutic concentration range were inputted.CONCLUSION: The method is applicable for any drug that was in line with one compartment model intermittent intravenous dosage regimen,and this method is rapid,simple,reliable and direct. |
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| Keywords: | Excel |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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