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血管回声跟踪技术对男性飞行员颈动脉血管弹性的定量检测
引用本文:李文秀,姚克纯,张龙方,李利,吴迪,刘淑萍,汪娜. 血管回声跟踪技术对男性飞行员颈动脉血管弹性的定量检测[J]. 中华航空航天医学杂志, 2010, 21(3). DOI: 10.3760/cma.j.issn.1007-6239.2010.03.008
作者姓名:李文秀  姚克纯  张龙方  李利  吴迪  刘淑萍  汪娜
作者单位:空军总医院超声科,北京,100142
基金项目:中国博士后科学基金面上资助项目,军队后勤科研基金 
摘    要:目的 通过血管回声跟踪(echo-tracking,ET)技术对颈动脉血管弹性的定量检测,探讨年龄及飞行时间对男性飞行员颈动脉血管弹性的影响. 方法 根据年龄将72例飞行员分为20~29岁(27人)、30~39岁(30人)和40~49岁(15人)3组.应用ET技术检测各组飞行员的颈动脉血管,并采用t检验分别对各个年龄组颈动脉血管弹性值[僵硬度(stiffness parameter,β)、弹性模量(pressure-strain elastic modulus,Ep)、顺应性(arterial compliance,AC)和脉搏波传导速度(pulse wave velocity calculated from β value,PWVβ)]与国人正常测量值(对照组)进行对比分析,采用方差分析对各组间血管弹性值和飞行时间进行比较,通过直线相关和偏相关分析对各组飞行员年龄与飞行时间对颈动脉血管弹性的影响进行分析. 结果 飞行员各组β、Ep及PWVβ均较国人正常测量值降低,AC增高.飞行员20~29岁及30~39岁组血管弹性值与其对照组比较,有统计学意义(t=2.061~6.712,P<0.05或P<0.01),40~49岁组与对照组比较,无统计学意义.通过直线相关分析,30~39岁组的年龄、飞行时间与β、Ep和PWVβ均存在显著正相关;在20~29岁和30~39岁组中,年龄与飞行时间存在显著性正相关(r=0.655、0.723,P=0.001、0.000).通过偏相关分析,在控制飞行时间因素时,30~39岁组中β和Ep值与年龄存在显著正相关(r=0.516、0.452,P=0.007、0.020),即随着年龄的增加,β和Ep值增加. 结论 年龄对男性飞行员颈动脉血管弹性影响较大,而飞行时间影响较小.ET技术对飞行员颈动脉血管弹性值的定量检测有助于进一步了解男性飞行员的血管功能状态.Abstract:Objective To investigate quantitative detection of the carotid elasticity of male pilots in different age groups by using echo-tracking (ET) technique. Methods The carotid arteries were detected by ET technique in 72 male pilots who were divided into 3 groups according to age. The elasticity values, including stiffness parameter (β), pressure-strain elastic modulus (Ep), arterial compliance (AC) and pulse wave velocity calculated from β value (PWVβ) were analyzed by t test.The elasticity values and flying hours were also processed by variance analysis among 3 groups. The influence of age and flying hours to elasticity values was resolved by linear correlation and partial correlation analysis. Results There was no difference on elasticity values of bilateral carotid. The arterial stiffness indices, such as β, Ep and PWVβ in each group, were lower than those by the normal measuring, but AC value was higher. By comparing with control group, the carotid elasticity values had statistical difference in 20-29 yrs and 30-30 yrs groups, but for 40-49 yrs group comparison there was no significant difference (t= 2. 061-6. 712, P<0.05 or P<0.01). Linear correlation analysis showed that age and flying hours appeared significant and positive correlation to β, Ep and PWVβ in 30-39 yrs group. In 20-29 and 30-39 yrs groups, age was significantly and positively correlated to flying hours (r=0. 655, 0. 723, P=0. 001, 0. 000). In 30-39 yrs group β and Ep were positively correlated with age based on partial correlation analysis (r= 0. 516, 0. 452, P= 0. 007, 0. 020), which meant that β and Ep significantly increased with age. Conclusions For male pilot age expresses greater influence than flying hours to carotid artery elasticity. Quantitatively detecting male pilot's carotid artery elasticity by ET technique will contribute to the delermination of pilot's artery functional status.

关 键 词:血管回声跟踪技术  男性飞行员  颈动脉血管  血管弹性  定量检测  male  carotid  artery  quantitative  detection  correlation  analysis  飞行时间  partial  correlation  linear  correlation  elastic  modulus  difference  wave  velocity  偏相关分析  age  significant  统计学意义  正相关

Quantitative detection of carotid artery elasticity by echo-tracking technique for male pilots
LI Wen-xiu,YAO Ke-chun,ZHANG Long-fang,LI Li,WU Di,LIU Shu-ping,WANG Na. Quantitative detection of carotid artery elasticity by echo-tracking technique for male pilots[J]. Chinese Journal of Aerospace Medicine, 2010, 21(3). DOI: 10.3760/cma.j.issn.1007-6239.2010.03.008
Authors:LI Wen-xiu  YAO Ke-chun  ZHANG Long-fang  LI Li  WU Di  LIU Shu-ping  WANG Na
Abstract:Objective To investigate quantitative detection of the carotid elasticity of male pilots in different age groups by using echo-tracking (ET) technique. Methods The carotid arteries were detected by ET technique in 72 male pilots who were divided into 3 groups according to age. The elasticity values, including stiffness parameter (β), pressure-strain elastic modulus (Ep), arterial compliance (AC) and pulse wave velocity calculated from β value (PWVβ) were analyzed by t test.The elasticity values and flying hours were also processed by variance analysis among 3 groups. The influence of age and flying hours to elasticity values was resolved by linear correlation and partial correlation analysis. Results There was no difference on elasticity values of bilateral carotid. The arterial stiffness indices, such as β, Ep and PWVβ in each group, were lower than those by the normal measuring, but AC value was higher. By comparing with control group, the carotid elasticity values had statistical difference in 20-29 yrs and 30-30 yrs groups, but for 40-49 yrs group comparison there was no significant difference (t= 2. 061-6. 712, P<0.05 or P<0.01). Linear correlation analysis showed that age and flying hours appeared significant and positive correlation to β, Ep and PWVβ in 30-39 yrs group. In 20-29 and 30-39 yrs groups, age was significantly and positively correlated to flying hours (r=0. 655, 0. 723, P=0. 001, 0. 000). In 30-39 yrs group β and Ep were positively correlated with age based on partial correlation analysis (r= 0. 516, 0. 452, P= 0. 007, 0. 020), which meant that β and Ep significantly increased with age. Conclusions For male pilot age expresses greater influence than flying hours to carotid artery elasticity. Quantitatively detecting male pilot's carotid artery elasticity by ET technique will contribute to the delermination of pilot's artery functional status.
Keywords:Ultrasonography  Carotid arteries  Elasticity
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