| 食欲素诱导结肠癌细胞凋亡机制的研究 |
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| 引用本文： | 张蓉,苏文涛,安楠,刘君,藤启凤,李兴梅,白飞虎,呼圣娟.食欲素诱导结肠癌细胞凋亡机制的研究[J].现代肿瘤医学,2017(21):3537-3540. |
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| 作者姓名： | 张蓉 苏文涛 安楠 刘君 藤启凤 李兴梅 白飞虎 呼圣娟 |
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| 作者单位： | 1. 宁夏医科大学,宁夏银川,750000;2. 宁夏人民医院消化内科,宁夏银川,750000 |
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| 基金项目： | 宁夏回族自治区重点研发计划项目(2016KJHM85)，宁夏自然科学基金项目(NZ15189) |
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| 摘 要： | 食欲素(orexin)是下丘脑分泌的一种新型神经肽,具有调节摄食行为、能量代谢、睡眠与觉醒等生理作用.近年来,多项研究证实食欲素可以促进肿瘤细胞的凋亡,尤以结肠癌细胞研究较多.本文欲从食欲素与结肠癌的研究现状及促进结肠癌细胞凋亡机制方面进行阐述.
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| 关 键 词： | 食欲素 食欲素受体 凋亡 结肠癌 |
The mechanism of apoptosis of colon cancer cells induced by orexin |
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| Zhang Rong,Su Wentao,An Nan,Liu Jun,Teng Qifeng,Li Xingmei,Bai Feihu,Hu Shengjuan.The mechanism of apoptosis of colon cancer cells induced by orexin[J].Journal of Modern Oncology,2017(21):3537-3540. |
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| Authors: | Zhang Rong Su Wentao An Nan Liu Jun Teng Qifeng Li Xingmei Bai Feihu Hu Shengjuan |
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| Abstract: | Orexin (OX) is a novel neuropeptide which secreted by the hypothalamus.It could regulate feeding behavior,energy metabolism,sleep and arousal,and so on.In recent years,a good number of studies have shown that orexin can promote malignant tumor cells apoptosis,especially in colon cancer cell.In this article,we decribe the present situation about relationship of orexin and colon cancer,mainly introduce the mechanism which orexin could induce apoptosis of colon cancer cell. |
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| Keywords: | orexin orexin receptor apoptosis colon cancer |
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