不同游泳时间对高脂饮食老年大鼠血浆脂蛋白、载脂蛋白的影响

目的 :观察不同强度游泳运动对老年高脂饮食大鼠血脂、脂蛋白和载脂蛋白的影响 ,从而了解不同强度运动对动脉粥样硬化的预防作用。方法 :15月龄、雄性SD大鼠在饲喂高脂饮食的同时进行长、短两种不同时间的游泳 ,持续 15周。结果 :大鼠进食 15周高脂膳食后形成了高胆固醇血症模型 ;运动使大鼠血浆HDL -C、ApoAI明显升高 (P <0 .0 1,P <0 .0 5 ) ,TG显著下降 (P <0 .0 5 ) ;低运动强度可刺激ApoAI增高 ,比大运动强度对改善血脂代谢紊乱更有效。结论 :低运动强度在预防饮食致血脂代谢紊乱引起的动脉粥样硬化方面有更好的效果

Swimming training and the changes of serum lipids, lipoproteins and apolipoproteins in rats with fed-caused hyperlipoproteinemia

Objective:In order to understand the effects of prevention of the different intensities for atherosclerosis , the changes of serum lipids, lipoproteins and apolipoproteins after swimming training for 15 weeks in rats were observed. Method: SD rats, male, 15 month years old, was randomly assigned to swimming training with 45min or 90min per day, which lasted 15 weeks. Training progressed with the high-fat feed at the same time. Result:Hypercholesterolemia in high-fat fed rats was established after 15 weeks; The serum HDL-C, ApoAI were significantly increased( P <0.01, P <0.05) and TG markedly decreased( P <0.05) in rats with intervention of exercise; low intensity exercise was better than higher intensity for improving the lipoprotein disorder through stimulating the increase of ApoAI in rats. Conclusion:Low intensity exercise has better effects on prevention of atherosclerosis for fed-caused hyperlipoproteinemia in rats.