脑梗死患者血清铁蛋白叶酸和维生素B12测定的临床意义

目的 :探讨脑梗死 (CI)患者血清铁蛋白 (SF)、叶酸和维生素B12 (VitB12 )水平的变化。方法 :对 4 1例急性CI患者、37例CI恢复期患者及 4 5例健康对照者采用全自动微粒子化学发光免疫分析仪测定了血清SF、叶酸和VitB12 水平。结果 :急性CI患者血清SF水平明显高于健康对照组 (P <0 0 1) ,而叶酸水平显著低于对照组 (P <0 0 1) ,VitB12 含量也低于对照组 (P <0 0 5 ) ,恢复期SF、叶酸和VitB12 水平与对照组比较无显著性差异 (P >0 0 5 )。结论 :SF、叶酸和VitB12 可能参与了CI的病理、生理过程 ,动态测定血清SF、叶酸和VitB12 有助于病情观察。

Clinical Significance of Serum Ferritin,Folate and Vitamin B12 levels in Patients with Cerebral Infarction

Objective: To study the changs of serum ferritin,folate and vitamin B 12 in the cerebral infarction (CI)group.Methods: Fourty one patients in acute CI group and 37 patients in recovery group with 45 healthy control group were investigated by means of chemiluminescent immunoassay for serum ferritin,folate and vitamin B 12.Results: The levels of serum ferritin in patients in acute CI group were dramatically higher than those in control group (P<0.01).Folate was significantly decrease in patients in acute CI group than those in control group (P<0.01),and vitamin B 12 was lower in patients in acute CI group than those in control group (P<0.05). There was no statistically significant difference between the control group and the recovery group in serum ferritin,folate and vitamin B 12 levels (P>0.05).Conclusion: It was suggested that ferritin,folate and vitamin B 12 could participate in the process of pathology and physiology in CI.Dynamic detection of serum ferritin,folate and vitamin B 12 was helpful to study the state of an illness in CI.