Ultrastructural Study of Chitosan Effects on Klebsiella and Staphylococci |
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| Authors: | L V Didenko D V Gerasimenko N D Konstantinova T A Silkina I D Avdienko G E Bannikova V P Varlamov |
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| Institution: | (1) Laboratory of Microorganism Anatomy, N. F. Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Russia;(2) Laboratory of Enzyme Engineering, Bioengineering Center, Russian Academy of Sciences, Moscow, Russia |
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| Abstract: | Antibacterial effect of chitosan on the morphofunctional organization of clinical strains of Klebsiella pneumoniae and Staphylococcus aureus was studied by transmission electron microscopy. Chitosan promoted aggregation of bacterial cells and disorganization of
bacterial cell wall and cytoplasmic membrane, which leads to the release of bacterial contents into the environment. These
structural changes result in bacterial death.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 9, pp. 343–347, September, 2005 |
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| Keywords: | Klebsiella pneumoniae Staphylococcus aureus chitosan ultrastructure |
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