| 鸡血藤有效成分研究 |
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| 引用本文： | 崔艳君,刘屏,陈若芸. 鸡血藤有效成分研究[J]. 中国中药杂志, 2005, 30(2): 121-123 |
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| 作者姓名： | 崔艳君 刘屏 陈若芸 |
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| 作者单位： | 1. 中国医学科学院,中国协和医科大学,药物研究所,北京,100050
2. 中国人民解放军总医院,北京,100853 |
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| 摘 要： | 目的 :研究鸡血藤原植物密花豆Spatholobus suberectus的有效成分。方法 :利用各种色谱技术进行分离纯化 ,根据理化性质和各种波谱技术进行结构鉴定。结果 :分离鉴定了 8个化合物 ,分别为芒柄花苷 (ononin ,1) ,樱黄素 (prunetin ,2 ) ,没食子儿茶素 (gallocatechin ,3) ,儿茶素 (catechin ,4 ) ,表儿茶素 (epicatechin ,5 ) ,丁香酸 (syringicacid ,6 ) ,香草酸 (vanillicacid ,7) ,胡萝卜苷 (daucosterol,8)。结论 :化合物 3,4 ,6 ,7为首次从密花豆属中分离得到。其中化合物 4对骨髓抑制小鼠造血祖细胞的增殖有刺激活性。
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| 关 键 词： | 鸡血藤 密花豆 没食子儿茶素 儿茶素 表儿茶素 |
| 文章编号： | 1001-5302(2005)02-0121-03 |
| 收稿时间： | 2003-07-30 |
Studies on the active constituents in vine stem of Spatholobus suberectus |
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| CUI Yan-jun;LIU Ping;CHEN Ruo-yun. Studies on the active constituents in vine stem of Spatholobus suberectus[J]. China Journal of Chinese Materia Medica, 2005, 30(2): 121-123 |
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| Authors: | CUI Yan-jun LIU Ping CHEN Ruo-yun |
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| Affiliation: | Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Bejing 100050 China. |
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| Abstract: | Objective: To study the active constituents in vine stem of Spatholobus suberectus. Method: The constituents of Spatholobus suberectus were systematically separated with various chromatographic techniques. The structures were elucidated by physico-chemical properties and spectral data. Result: Eight compounds were isolated from S. suberectus, and were identified as: ononin (1), pruneitin (2), gallocatechin (3), catechin (4), epicatechin (5), syringic acid(6), vanillic acid(7) and daucosterol(8). Conclusion: Compound 3,4,6,7 were obtained from Spatholobus genus for the first time. Compound 4 has stimulation to proliferation of hematopoietic progenitor cell. |
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| Keywords: | Caulis Spatholobi Spatholobus suberectus gallocatechin catechin epicatechin |
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