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恩丹西酮预防小儿氯胺酮麻醉围术期恶心呕吐的临床研究
引用本文:孙波,李文志,姜长文,那北雁. 恩丹西酮预防小儿氯胺酮麻醉围术期恶心呕吐的临床研究[J]. 黑龙江医学, 2000, 0(6): 3-4
作者姓名:孙波  李文志  姜长文  那北雁
作者单位:1. 哈尔滨医科大学附属第二临床医学院
2. 郎乡林业局职工医院
3. 哈尔滨市骨伤医院
摘    要:目的 :应用恩丹西酮预防小儿氯胺酮麻醉围术期恶心、呕吐的发生率。方法 :随机选择 30例小儿唇裂整形术患儿 ,分为恩丹西酮组 ( 1 5例 )和对照组 ( 1 5例 ) ,全部采用氯胺酮麻醉。氯胺酮给药 1 0min后 ,经静脉缓慢注入恩丹西酮或安慰剂进行双盲法研究 ;结果 :安慰剂组恶心、呕吐发生率为 2 0 %、5 3 33% ;恩丹西酮组恶心、呕吐发生率为 2 6 7%、6 6 7% (P <0 0 5 ) ;结论 :恩丹西酮适用小儿氯胺酮麻醉围术期恶心呕吐的预防

关 键 词:恩丹西酮  氯胺酮  麻醉  恶心  呕吐

Clinical Study on Prevention of Nausea and Vomiting during Children Anesthesia with Ketamine Perioperatively with Ondansetron
Sun Bo Jiang Changwen Li Wenzong The Second Affiliated Hospital of Harbin Medical University. Clinical Study on Prevention of Nausea and Vomiting during Children Anesthesia with Ketamine Perioperatively with Ondansetron[J]. Heilongjiang Medical Journal, 2000, 0(6): 3-4
Authors:Sun Bo Jiang Changwen Li Wenzong The Second Affiliated Hospital of Harbin Medical University
Affiliation:Sun Bo Jiang Changwen Li Wenzong The Second Affiliated Hospital of Harbin Medical University
Abstract:Objective:To assess the effects of ondansetron on the prevention of perioperative nausea and vomiting when children were taken with ketamine anesthesia.Methods;A randomized,double blind and placebo-controlled trial of 30 children were studied.They were scheduled for cheiloplastic operation with ketamine anesthesia and 10 minutes later ondansetron (test group) or 5% glucose was injected intravenously (placebo group).Results:The nausea and vomiting recurrence rate were 26.57% and 6.67% in test group respectively and 20% and 53.33% in placebo group(p<005).Conclusion:The administration of ondansetron intravenously could be an effective prevention for perioperative nausea and vomiting when ketamine anesthesia inchildren.
Keywords:Ondansetron Ketamine Anesthesia Nausea Vomiting
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