经直肠超声下的前列腺低回声区及其临床意义

目的评估经直肠超声下的前列腺低回声区及其临床意义。方法1999年8月~2004年8月,共438例患者接受了经直肠超声引导前列腺系统穿刺活检术,活检点数为6~13点。如果经直肠超声检查发现前列腺的低回声区,亦加取该区部位的活检。将低回声区、等回声区的活检结果进行比较。结果总的癌检出率为25.6%(112/438)。112例前列腺癌患者中,有低回声区者75例,占67%,无低回声区者37例,占33%。本组总共取得3504个活检点,取自低回声区者636个。636个低回声区中癌区163个,占25.6%,非癌区473个,占74.4%。腺体中有或无低回声区检出前列腺癌的可能性相当,为25.2%(75/298)和26.4%(37/140),差异无统计学意义(P>0.05)。结论多数前列腺癌可发现低回声区,但多数低回声区并非前列腺癌。腺体中有无低回声区对前列腺癌的检出率相当。

Clinical significance of prostatic hypoechoic lesions on ultrasonography

Objective To evaluate the clinical significance of prostatic hypoechoic lesions on transrectal ultrasound (TRUS) for prostate cancer detection.Methods Four hundred and thirty-eight patients referred for biopsy of the prostate from August 1999 to August 2004. Every patient received 6-13 biopsy cores of the prostate. If a hypoechoic was identified, the biopsy was taken from this lesion. Correlation between hypo-echoic lesions, isoechoic areas and cancer detection for each core was performed. Results Among 438 patients, cancer was detected in 112(25.6%). Hypo-echoic lesions were seen in 75 (67%) patients with prostate cancer, the isoechoic were as in 37 (33%). A total of 3504 biopsy cores were obtained from 438 patients, and 636 biopsy cores were taken from hypoechoic lesions. Among 636 biopsy cores, 163 (25.6%) were cancer and 473(74.4%)were not. The cancer detective rate in patients with hypoechoic lesions (75/298, 25.2%) was similar to non-hypoechoic lesions (37/140, 26.4%) on TRUS. There was no statistically significant difference between them (P<0.05). Conclusions Most patients with prostate cancer have hypoechoic lesions on TRUS, but most hypoechoic lesions on TRUS are not prostate cancer. The cancer detective rate in patients with hypoechoic lesion is similar to non-hypoechoic lesions on TRUS.