Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death

Authors:	Yao Jia-Wei Liu Jing Kong Xiang-Zhen Zhang Shou-Guo Wang Xiao-Hui Yu Miao Zhan Yi-Qun Li Wei Xu Wang-Xiang Tang Liu-Jun Ge Chang-Hui Wang Lin Li Chang-Yan Yang Xiao-Ming

Affiliation:	^a Tianjin University, School of Chemical Engineering and Technology, Department of pharmaceutical engineering, Tianjin 300072, China ^b Beijing Institute of Radiation Medicine, Beijing 100850, China ^c State Key laboratory of Proteomics, Beijing 100850, China

Abstract:

Keywords:	Keap1, kelch-like ECH-associated protein 1 Nrf2, nuclear factor (erythroid-derived 2)-like 2 Cul3, Cullin-3 ARE, antioxidant response element GSH, glutathione SOD, superoxide dismutase HO-1, heme oxygenase 1 NQO1, NAD(P)H:quinone oxidoreductase 1 Ub, ubiquitin PMID, 3-(3-Pyridylmethylidene)-2-Indolinone 6-OHDA, 6-Hydroxydopamine hydrobromide PBS, phosphate-buffered saline
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