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温针灸结合穴位按摩对胃癌患者术后血清胃泌素、胃动素及胃肠功能的影响
引用本文:吴静,张昊,毛菲.温针灸结合穴位按摩对胃癌患者术后血清胃泌素、胃动素及胃肠功能的影响[J].中国临床研究,2021(2).
作者姓名:吴静  张昊  毛菲
作者单位:西安交通大学第一附属医院肿瘤外科;西安交通大学第一附属医院康复科
基金项目:国家自然科学基金:(81502442)。
摘    要:目的探讨温针灸结合穴位按摩对胃癌患者术后血清胃泌素、胃动素水平及胃肠功能的影响。方法以2018年4月至2019年11月收治的98例胃癌手术患者为研究对象,按随机数字表法分为观察组(49例)和对照组(49例)。对照组采用术后常规处理,观察组在对照组基础上进行温针灸结合穴位按摩治疗,两组均持续治疗7 d。对比两组术后胃肠功能恢复时间、住院时间、并发症发生情况,术前、术后7 d的血常规指标、血清胃肠激素水平。结果观察组患者肠鸣音恢复时间、肛门排气时间、首次排便时间以及术后住院时间短于对照组,差异有统计学意义(P<0.01)。术后7 d时,两组血清胃泌素、胃动素、血管活性肠肽(VIP),全血白细胞(WBC)、中性粒细胞计数(NEU)较术前升高,且观察组高于对照组(P<0.05,P<0.01)。术后7 d时,观察组全血淋巴细胞计数(LYM)较术前升高,对照组较术前降低,观察组高于对照组(P<0.05,P<0.01)。观察组术后并发症总发生率低于对照组(14.29%vs 32.65%,χ2=4.602,P<0.05)。结论温针灸结合穴位按摩可改善胃癌术后患者胃肠激素水平,促进术后胃肠道功能的恢复,缩短住院治疗时间,同时可调节机体免疫,降低并发症发生率。

关 键 词:温针灸  穴位按摩  胃癌  胃泌素  胃动素  胃肠功能

Effects of warm acupuncture combined with acupoint massage on serum gastrin,motilin level and gastrointestinal function in patients with gastric cancer after operation
WU Jing,ZHANG Hao,MAO Fei.Effects of warm acupuncture combined with acupoint massage on serum gastrin,motilin level and gastrointestinal function in patients with gastric cancer after operation[J].Chinese Journal of Clinical Research,2021(2).
Authors:WU Jing  ZHANG Hao  MAO Fei
Institution:(Department of Oncology Surgery,the First Affiliated Hospital of Xi′an Jiaotong University,Xi'an,Shaanxi 710061,China)
Abstract:Objective To explore the effect of warm acupuncture combined with acupoint massage on serum gastrin(GAS),motilin(MOT)levels and gastrointestinal function in patients with gastric cancer after surgery.Methods Between April 2018 and November 2019,98 patients with gastric cancer undergoing surgery were divided into observation group(49 cases)and control group(49 cases)according to random number table method.The control group was treated with conventional treatment after surgery,and the observation group was treated with warm acupuncture and acupoint massage on the basis of the control group.Both groups were treated for 7 d.The postoperative gastrointestinal function recovery time,hospital stay,and complications after surgery of the two groups were compared.The blood routine indexes and serum gastrointestinal hormone levels before and 7 d after surgery were compared between the two groups.Results The postoperative bowel sound recovery time,anal exhaust time,first defecation time,and postoperative hospital stay in observation group were significantly shorter than those in control group(P<0.01).At 7 d after surgery,the serum GAS,MOT,vasoactive intestinal peptide(VIP),WBC and NEU in the whole blood levels of the two groups were higher than those before the surgery,and those in observation group was higher than in control group(P<0.05,P<0.01).At 7 d after surgery,the number of whole blood LYM in observation group were significantly higher,the control group was significantly lower,and in observation group was higher than in control group(P<0.05,P<0.01).The incidence of postoperative complications in the observation group was lower than that in control group(14.29%vs 32.65%,χ2=4.602,P<0.05).Conclusion Warm acupuncture combined with acupoint massage can improve gastrointestinal hormone levels in patients with gastric cancer surgery,promote recovery of postoperative gastrointestinal function,and shorten the length of hospitalization,regulate body immunity,reduce the incidence of complications.
Keywords:Warm acupuncture  Acupoint massage  Gastric cancer  Gastrin  Motilin  Gastrointestinal function
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