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阿托伐他汀钙治疗老年脑动脉硬化的效果及对患者TC、TG、HDL-C、LDL-C水平的影响观察
引用本文:孟馨,赵萍. 阿托伐他汀钙治疗老年脑动脉硬化的效果及对患者TC、TG、HDL-C、LDL-C水平的影响观察[J]. 中国实用医药, 2021, 0(6): 1-3
作者姓名:孟馨  赵萍
作者单位:辽宁中置盛京老年病医院有限公司干诊病房;沈阳体育学院门诊部内科
摘    要:目的 分析阿托伐他汀钙治疗老年脑动脉硬化的效果及对患者总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平的影响.方法 70例老年脑动脉硬化患者,随机分为对照组和观察组,各35例.对照组患者采取常规药物治疗,观察组在对照组基础上增加阿托伐他汀钙治疗.比较两组开始用药...

关 键 词:老年脑动脉硬化  阿托伐他汀钙  丁苯酞

Efficacy of atorvastatin calcium in the treatment of senile cerebral arteriosclerosis and its influence on the levels of TC,TG,HDL-C and LDL-C
MENG Xin,ZHAO Ping. Efficacy of atorvastatin calcium in the treatment of senile cerebral arteriosclerosis and its influence on the levels of TC,TG,HDL-C and LDL-C[J]. China Practical Medical, 2021, 0(6): 1-3
Authors:MENG Xin  ZHAO Ping
Affiliation:(Liaoning Zhongzhi Shengjing Geriatric Hospital Co.,Ltd.,Shenyang 110000,China)
Abstract:Objective To analyze the efficacy of atorvastatin calcium in the treatment of senile cerebral arteriosclerosis and its influence on the levels of total cholesterol(TC),triglycerides(TG),highdensity lipoprotein cholesterol(HDL-C),and low-density lipoprotein cholesterol(LDL-C).Methods A total of 70 cases of senile cerebral arteriosclerosis were randomly divided into contrl group and observation group,with 35 cases in each group.The control group was treated with conventional drugs,and the observation group was treated with atorvastatin calcium based on the control group.The onset time,hospitalization time,levels of TC,TG,HDL-C and LDL-C before and after treatment,treatment effect and the occurrence of adverse reactions were compared between the two groups.Results The onset time and hospitalization time of the observation group were(7.43±1.71)and(9.12±2.34)d,which were all shorter than(8.78±2.21)and(10.42±2.78)d of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of TC,TG and LDL-C of the observation group were lower than those of the control group,and HDL-C was higher than that of the control group.The difference was statistically significant(P<0.05).The total effective rate of treatment 94.29%of the observation group was higher than 74.29%of the control group,and the difference was statistically significant(χ2=5.285,P<0.05).There was no statistically significant difference in incidence of adverse reactions between the two groups(χ2=0,P>0.05).Conclusion Atorvastatin calcium has affirmative effect on the treatment of senile cerebral arteriosclerosis,which can effectively regulate the level of blood lipids in senile patients with cerebral arteriosclerosis and improve the therapeutic effect with high safety and no obvious side effects.It is worth popularizing and applying.
Keywords:Senile cerebral arteriosclerosis  Atorvastatin calcium  Butylphthalide
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