| 枯草杆菌二联活菌肠溶胶囊联合莫沙必利对长航人员功能性便秘疗效观察 |
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| 引用本文： | 吕伟,李艳君,夏菁,孙涛. 枯草杆菌二联活菌肠溶胶囊联合莫沙必利对长航人员功能性便秘疗效观察[J]. 转化医学杂志, 2017, 6(2): 103-105 |
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| 作者姓名： | 吕伟 李艳君 夏菁 孙涛 |
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| 作者单位： | 第二军医大学,海军总医院检验科,海军总医院特需医疗部,海军总医院特需医疗部 |
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| 基金项目： | 军队后勤科研计划（CHJ11J018） |
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| 摘 要： | 目的探讨长航人员功能性便秘（functional constipation，FC）的患病情况及枯草杆菌二联活菌肠溶胶囊联合莫沙必利干预性治疗的效果观察。方法采用整群分层抽样方法分别于长航前后对1 298名任务官兵进行问卷调查，调查问卷采用罗马Ⅲ标准流行病学调查问卷，有180例诊断为FC，随机分为联合治疗组（枯草杆菌二联活菌肠溶胶囊联合莫沙必利治疗，83例）和对照组（单纯用莫沙必利治疗，97例）。结果任务官兵FC患病率高达13.87%，经过药物治疗后2组便秘症状均有明显改善；同组比较观察指标较治疗前均明显改善，差异有统计学意义（P＜0.001）。组间比较，联合治疗组较对照组改善更为明显，差异有统计学意义（P＜0.001）。联合治疗组总有效率为91.57%，对照组总有效率为62.89%，2组比较差异有统计学意义（P＜0.001）。结论枯草杆菌二联活菌肠溶胶囊联合莫沙必利对长航官兵FC治疗疗效显著，值得临床推广。
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| 关 键 词： | 功能性便秘；疗效；长航 |
Effect of live combined b.subtilis and e.faecium enteric coated capsules combined with mosapride on functional constipation and analysis of clinical observation in personnel undertaking long voyage |
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| Lv Wei,LI Yanjun,XIA Jing and SUN Tao. Effect of live combined b.subtilis and e.faecium enteric coated capsules combined with mosapride on functional constipation and analysis of clinical observation in personnel undertaking long voyage[J]. Translational Medicine Journal, 2017, 6(2): 103-105 |
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| Authors: | Lv Wei LI Yanjun XIA Jing SUN Tao |
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| Affiliation: | The Second Military Medical University, Shanghai 200433, China,Department of Laboratory, Medical School of Xiangya, Central South University,,Department of Clinical Laboratory, Navy General Hospital, Beijing 100048, China and Department of Clinical Laboratory, Navy General Hospital, Beijing 100049, China |
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| Abstract: | |
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| Keywords: | Functional constipation (FC) Clinical observation Long voyage deployment at sea |
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