| 补阳还五汤对动脉粥样硬化大鼠模型C反应蛋白的影响 |
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| 引用本文： | 陈燕清,张红珍. 补阳还五汤对动脉粥样硬化大鼠模型C反应蛋白的影响[J]. 中国中医急症, 2011, 20(4): 592-593 |
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| 作者姓名： | 陈燕清 张红珍 |
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| 作者单位： | 山西中医学院,山西,太原,030024 |
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| 基金项目： | 山西省卫生厅科技攻关项目 |
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| 摘 要： | 目的利用高脂饲料诱发的动脉粥样硬化（AS）模型,观察补阳还五汤对C反应蛋白（CRP）的影响。方法大鼠造模成功后,随机分为4组：补阳还五汤组以补阳还五汤17.5g/（kg.d）灌胃;川芎嗪组给予川芎嗪0.2 g/（kg.d）灌胃;正常组及模型组喂普通饲料。用药30d后测定CRP、血脂。结果高脂饮食可诱导大鼠形成AS模型,模型组的血脂明显高于正常组。补阳还五汤组CRP、总胆固醇、甘油三酯、低密度脂蛋白水平均显著低于川芎嗪组、模型组。结论补阳还五汤具有抗AS作用,降低CRP和血脂可能是其作用机制之一。
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| 关 键 词： | 动脉粥样硬化 补阳还五汤 C反应蛋白 益气活血 |
Effect of Buyanghuanwu Decoction on C Reactive Protein of Rats Model with Atherosclerosis |
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| CHEN Yan-ging,ZHANG Hong-zhen. Effect of Buyanghuanwu Decoction on C Reactive Protein of Rats Model with Atherosclerosis[J]. Journal of Emergency in Traditional Chinese Medicine, 2011, 20(4): 592-593 |
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| Authors: | CHEN Yan-ging ZHANG Hong-zhen |
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| Affiliation: | CHEN Yan-qing,ZHANG Hong-zhen Shanxi University of Traditional Chinese Medicine(Taiyuan 030024,Shanxi) |
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| Abstract: | Objective:To observe the effect of Buyanghuanwu Decoction on C reactive protein(CRP) of atherosclerosis(AS) rat model induced by high fat diet.Methods:After the AS rats model establishement,these rats were divided randomly into 4 groups including the Buyanghuanwu Decoction group,the tetramethylpyrazine group,the normal control group and the model group.After 30 days,the CRP and the blood-lipid were detected.Results:The AS model was induced by the high fat diet.The concentration of blood-lipid in the model g... |
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| Keywords: | Atherosclerosis Buyanghuanwu Decoction C reactive protein Supplementing qi and activating blood |
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