| 喘息儿童胃食管连接部功能和酸反流的关系 |
| |
| 引用本文： | 罗燕军,胡赤军,鲁明.喘息儿童胃食管连接部功能和酸反流的关系[J].临床荟萃,2011,26(9):769-771. |
| |
| 作者姓名： | 罗燕军 胡赤军 鲁明 |
| |
| 作者单位： | 湖南省妇幼保健院,儿内科,湖北,武汉,430070 |
| |
| 摘 要： | 目的探讨胃食管连接部（EGJ）屏障功能在喘息儿童酸反流发病机制中的作用。方法选取有典型喘息症状的儿童74例行24小时食管pH监测和食管测压。根据pH〈4总时间百分比〈4%且Boix-Ochoa计分〈11.99的标准,将受试者分为胃食管反流组（pH＋组）和非胃食管反流组（pH-组）。结果喘息儿童胃食管反流发生率为66.2%（49/74）,pH＋组儿童食管pH监测的各项参数均明显高于pH-组儿童。胃食管连接部（EGJ）功能指标中,pH＋组食管下括约肌压力（LESP）低于pH-组（12.1±6.8）mmHg vs（33.5±5.6）mmHg（P〈0.05）。pH＋组平静呼吸时的膈脚压（CDP）、EGJ压（EGJP）及与吞咽相关的LES松弛后收缩波幅（post-LESRA）均低于pH-组（14.6±8.4）mmHg vs（21.3±10.3）mmHg（P〈0.05）,（28.6±11.1）mmHg vs（38.0±14.5）mmHg（P〈0.05）,（37.0±18.9）mmHg vs（71.8±17.2）mmHg（P〈0.05）。结论喘息儿童酸反流发生率高,与其EGJ抗反流功能减弱相关。
|
| 关 键 词： | 哮喘 胃食管反流 儿童 |
Barrier function of esophagogastric junction and acid reflux in children with wheezing |
| |
| LUO Yan-jun,HU Chi-jun,LU Ming.Barrier function of esophagogastric junction and acid reflux in children with wheezing[J].Clinical Focus,2011,26(9):769-771. |
| |
| Authors: | LUO Yan-jun HU Chi-jun LU Ming |
| |
| Institution: | LUO Yan-jun,HU Chi-jun,LU MingDepartment of Padiatrics,Hubei Maternal and Child Health Hospital,Wuhan 430070,China |
| |
| Abstract: | Objective To investigate the correlation between the barrier function of esophagogastric junction(EGJ) and acid reflux in children with wheezing.Methods A total of 74 children with wheezing were recruited and evaluated by 24-h pH monitoring and esophageal manometry.The children with wheezing were divided into reflux group(pH+ group) and non-reflux group(pH-group) in accordance with the criteria of the total percentage time of pH below 4 less than 4% and Boix-Ochoa score <11.99.Results In the group of wheezi... |
| |
| Keywords: | asthma gastroesophageal reflux child |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
