50例双胎输血综合征妊娠结局分析

目的探讨双胎输血综合征frrrs）的妊娠结局。方法将双胎输血综合征组（50例）作为研究组，将非双胎输血综合征组作为对照组（共104例）。比较两组间的年龄、孕次、受孕方式、早产率、新生儿窒息率、新生儿脑损伤率、胎儿丢失率、新生儿体重及妊娠期并发症发生率有无显著性差异。结果妊娠期高血压疾病、胆汁瘀积综合征、心力衰竭及贫血的发生例数两组差异无统计学意义（P〉0．05）。胎膜早破的发生例数两组差异有统计学意义（P〈0．05）。终止妊娠平均孕周、新生儿窒息率、新生儿脑损伤发生率、新生儿体重、胎儿丢失率、围生期死亡率差异有统计学意义（P〈0．05）。结论双胎输血综合征有更差的新生儿结局，需要进一步关注研究以改善新生儿预后。

Analysis of the pregnancy outcome of 50 cases with twin to twin transfusion syndrome

Objective To study the pregnancy outcome of the twin to twin transfusion syndrome （TITS）. Methods TTTS twins （n=50） were taken as the research group, and the non-TTTS twins （n=104） as the control group. The comparison between the two groups was made to detect significant differences on ages, gravidity, conceiving methods, preterm birth rates, asphyxia neonatorum rates, neonatal brain injury rates, fetal loss rates, neonatal weight, and pregnancy complications rates. Results There was no statistical significance in the differences between the incidence of gestational hypertension, intrahepatic cholestasis syndrome, heart failure, and anemia in the two groups（P〉0.05）. There was statistical significance in the differences of between the two groups in the occurred cases of premature rupture of membranes （P〈0.05）. The differences had statistical significance in the average gestational age＇of pregnancy termination, asphyxia neonatorum rates, incidence of neonatal brain injury, neonatal weight, incidence of fetal loss and perinatal mortality （P〈0.05）. Conclusion The newborn outcome of TITS is worse than non-TITS, and it requires further attention and research to improve the neonatal prognosis.