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Endomyometriosis arising in the uterosacral ligament: a case report including a literature review and immunohistochemical analysis
Authors:Matsuzaki S  Murakami T  Sato S  Moriya T  Sasano H  Yajima A
Affiliation:Departments of Obstetrics and Gynecology andPathology, Tohoku University School of Medicine, Sendai, Japan. matsuzaki@ob-gy.med.tohoku.ac.jp
Abstract:We report a case of endomyometriosis arising in the left uterosacral ligament of a 29-year-old woman. The central cavity of the uterine-like mass was lined by pseudo-stratified columnar epithelium and endometrial stroma. The wall of the cyst consisted of bundles of smooth muscle cells. Immunohistochemical analysis demonstrated both alpha-estrogen receptor and progesterone receptor immunoreactivities in the epithelial, stromal and smooth muscle cells. A relatively high proliferating activity was also demonstrated in these cells by Ki-67 immunostaining. These findings suggest that the mass was hormone dependent and had a relatively rapid evolution.
Keywords:congenital malformation    endomyometriosis    immunohistochemistry    metaplasia
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