加替沙星7日疗法治疗43例急性尿路感染的临床评价

目的：评价加替沙星治疗急性尿路感染的有效性和安全性.方法：将86例临床确诊为急性尿路感染的患者随机分为2组：试验组（加替沙星组）43例,口服加替沙星胶囊400 mg,1次/d;对照组（头孢克洛组）43例,口服头孢克洛胶囊250 mg,3次/d,疗程均为1周.结果：试验组与对照组总有效率分别为95.3%和93.o%.细菌清除率分别为94.6%和88.6%.药物不良反应发生率分别为7.0%和9.3%.结论：加替沙星7日疗法是治疗急性尿路感染安全、有效的临床治疗方法之一.

Clinical evaluation of gatifloxacin treatment for 7 days in 43 patients with acute urinary tract infection

Objective: To evaluate the effectiveness and safety of gatifloxacin compared with cefaclor in the treatment of acute urinary tract infection.Methods: Eighty-six patients with acute urinary tract infection were randomized into gatifloxacin group(GAT,400 mg,po,qd) and cefaclor group(CEF,250 mg,po,tid).Each group had 43 patients.The therapy lasted 7 days.Results: The overall clinical effective rates of GAT and CEF groups were 95.3% and 93.0%,respectively.The bacteria clearance rates of two groups were 94.6% and 88.6%,and the incidences of adverse drug reactions were 7.0% and 9.3%,respectively.Conclusion: Gatifloxacin treatment for 7 days is one of the safe and effective methods for treating acute urinary tract infection.