南京市儿童鼻-鼻窦炎性疾病与支气管哮喘相关性流行病学调查

目的:了解儿童鼻-鼻窦炎性疾病与支气管哮喘相关性流行病学特征。方法:2004年3~9月,用“南京市儿童呼吸道疾病问卷调查表”,对随机选择的南京市7所小学3年级学生(9~10岁)进行问卷调查。根据诊断标准对问卷中有相关症状者,由专科医师进行集中检查,结果进行统计学处理。结果:共发放问卷调查表1087份,回收989份,应答率91%,有效答卷942份。9~10岁儿童慢性鼻-鼻窦炎(慢性鼻-鼻窦炎组)发病率为8.8%,其中男9.1%,女8.5%;变应性鼻炎(变应性鼻炎组)发病率为5.1%,其中男5.6%,女4.6%,两者发病率与性别差异无统计学意义(P>0.05)。支气管哮喘总发病率为5.3%,其中男6.8%,女3.7%,男、女发病率差异有统计学意义(χ2=4.518,P<0.05)。慢性鼻-鼻窦炎并发支气管哮喘发病率为19.3%,变应性鼻炎并发支气管哮喘发病率为39.6%,均较无鼻疾病者(无鼻病组)的发病率(1.8%)高,支气管哮喘在慢性鼻-鼻窦炎和变应性鼻炎组中发病率明显升高,均差异有统计学意义(均P<0.01)。结论:支气管哮喘在鼻-鼻窦炎性疾病儿童中的发病率明显升高。

The epidemic survey of children rhinosinal inflammatory diseases and their correlation with asthma in Nanjing

Objective:To realize the epidemic features of rhinosinal inflammatory diseases in children and their correlation with asthma in Nanjing,China.Method:A questionnaire survey on children chronic rhinosinusitis (CRS) and airway diseases was conducted among 1087 elementary school children, aged from 9 to 10, of seven schools in Nanjing city by random cluster sampling, from March to September, 2004. The questionnaires include such questions as age, gender, family history, basis diseases, inducements, environment, therapy, correlative lower airway diseases and so on. The survey included screening suspects of CRS and allergic rhinitis (AR) by filling up the questionnaires by their parents and then special examination for accurate diagnosis. The information of asthma of children was obtained by inquiring whether children were diagnosed by physician in last 12 months. The results were dealt with statistics.Result:Nine hundred and eighty nine questionnaires were returned. The response rate was 91% and 942 questionnaires were available. The prevalence rate of CRS of children aged from 9 to 10 was 8.8% in Nanjing city. The prevalence rate of AR was 5.1%. The prevalence rate of asthma of children was 5.3% . The incidences of asthma of children with CRS and AR were 19.3% and 39.6%respectively , while that of children without rhinosinal inflammatory diseases was 1.8%. The results showed that the differences of the incidences of asthma between children with CRS, AR and without rhinosinal inflammatory diseases were statistically significant(P<0.01).Conclusion:Chronic rhinosinusitis is a common disease in children. The prevalence rates of CRS and AR in children aged from 9 to 10 in Nanjing city were 8.8% and 5.1%. The incidence of asthma in children with rhinosinal inflammatory diseases is markedly higher than that in children without these diseases.