| 缓减近视发展药物的新进展 |
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| 引用本文： | 赵炜,徐渊,惠延年. 缓减近视发展药物的新进展[J]. 眼视光学杂志, 2004, 6(1): 59-61,65 |
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| 作者姓名： | 赵炜 徐渊 惠延年 |
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| 作者单位： | 第四军医大学西京医院,全军眼科研究所,陕西,西安,710032 |
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| 摘 要： | 迄今的研究表明，利用药物疗法可望减缓青少年近视的发展。其中已应用的主要药物有睫状肌麻痹剂、降眼压药物、多巴胺等。已经证实胆碱能受体阻断剂能够显著地减缓近视发展，阿托品是代表性的药物，但其不可避免的副作用限制了它的使用。派伦西平作为选择性的M1受体阻断剂表现出引人关注的发展前景。寻找有效减缓近视发展、应用方便、毒副作用轻微的药物或方法，已成为近视研究的热点
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| 关 键 词： | 近视 干预 阿托品 哌仑西平 药物疗法 |
| 文章编号： | 1008-1801(2004)01-0059-04 |
Pharmacological interventions to slow myopia progression |
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| ZHAO Wei,XU Yuan,HUI Yan nian. Pharmacological interventions to slow myopia progression[J]. Chinese Journal of Optometry & Ophthalmology, 2004, 6(1): 59-61,65 |
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| Authors: | ZHAO Wei XU Yuan HUI Yan nian |
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| Affiliation: | ZHAO Wei,XU Yuan,HUI Yan nian. Xijing Hospital of the Fouxth Military Medical College,Xi'an China,710032 |
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| Abstract: | It has been shown that several classes of drugs,such as cycloplegics,ocular hypotensives,and dopamine,can be used to slow the progression of myopia,especially in adolescents. The most typical one,atropine,has been proven to be significantly effective,but unavoidable side effects limit its extensive use. At present,pirenzepine as the M 1 selective muscarinic antagonist is promising. Future projects should aim to discover agents with high efficacy,easy administration,and minimal side effects. |
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| Keywords: | myopia intervention atropine pirenzepine |
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