Bleomycin, vincristine, mitomycin-C, and cisplatin in the management of gynecological squamous cell carcinomas |
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| Authors: | Jerome L Belinson MD James A Stewart MD Audrey L Richards BA Maura McClure RN |
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| Institution: | 1. Department of Obstetrics and Gynecology of the Medical Center Hospital of Vermont, Vermont Regional Cancer Center University of Vermont College of Medicine, Burlington, Vermont 05401 USA;2. Department of Medicine, Medical Oncology Unit, University of Vermont College of Medicine, Vermont Regional Cancer Center University of Vermont College of Medicine, Burlington, Vermont 05401 USA;3. Department of Obstetrics and Gynecology of the Medical Center Hospital of Vermont, University of Vermont College of Medicine, Burlington, Vermont 05401 USA |
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| Abstract: | Twenty-one patients with squamous carcinoma of the genital tract were treated with bleomycin, Oncovin, mitomycin-C, and cisplatin (BOMP). Six patients received BOMP as primary therapy. Five of six responded with one patient having an autopsy-proven complete response after treatment for a disseminated adenosquamous carcinoma. Eight patients were treated for early recurrence, none responded. Seven patients were treated for late recurrences and one responded. We believe that BOMP has significant potential for primary treatment, but not for early or late recurrent disease. |
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| Keywords: | Chem chemotherapy Rad radiotherapy Surg surgery CR complete response PR partial response PD progressive disease SD stable disease A alive D dead |
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