Dynamic T1 functional MRI examinations with use of blood pool contrast agent--an approach to optimization of the technique期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Dynamic T1 functional MRI examinations with use of blood pool contrast agent--an approach to optimization of the technique

Authors:	Majos Agata Wolak Tomasz Sapieha Michał Olszycki Marek Bogorodzki Piotr Stefańczyk Ludomir

Affiliation:	^a Radiology Dep., Medical University of Lodz, Poland, 90-153 Lodz, Kopcinskiego 22 ^b Institute of Radioelectronics, Warsaw University of Technology, Poland, 00-665 Warsaw, Nowowiejska 15/19 ^c Institute of Physiology and Pathology of Hearing, Warsaw, Poland, 01-943 Warsaw, Pstrowskiego 1

Abstract:	The goal was to optimize dynamic T1 imaging for functional MRI (fMRI) examinations.For each of the 10 healthy subjects T1 3D gradient echo sequence (GRE) sequences were provided immediately after administration of blood pool contrast agent then every 2 h when subjects performed block finger tapings.Dynamic T1 fMRI is sensitive to detect cortical activations up to 6 h after BPCA administration. fMRI should be conducted within 2 h of CA administration, which is enough time for a typical fMRI experiment procedure.

Keywords:	Blood oxygenation level-dependent effect CBV Functional MRI Contrast media
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