Social support,stigma, and the mediating roles of depression on self-reported medication adherence of HAART recipients in China |
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| Authors: | Man Jiang Jiezhe Yang Yang Song Jinlei Zheng Xinghui Li Guang Yang |
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| Affiliation: | 1. School of Public Health/ Key Lab of Health Technology Assessment, National Health and Family Planning Commission of the People’s Republic of China, Fudan University, Shanghai, People’s Republic of China;2. Department of AIDS/STDs Control and Prevention, Zhejiang CDC, Hangzhou, People’s Republic of China;3. Department of Medical Affairs, Eye &4. Ent Hospital of Fudan University, Shanghai, People’s Republic of China |
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| Abstract: | Discrimination of people living with HIV/AIDS (PLWHA) is a persistent issue in China, which affects their psychological health. However, the association between psychological factors and adherence to highly active antiretroviral therapy (HAART) has not been systematically investigated before. Therefore, this study examined the impact of social support, depression, and medication-taking self-efficacy on ART adherence among PLWHA based on Cha et al.’s model, and included “stigma” to the original model to explain the psychological mechanism. Of the 504 participants receiving HAART, 37.8% had mild-to-severe depression. According to structural equation modeling, social support was directly associated with depression, stigma, and adherence; depression partially mediated the positive relationship between social support and adherence self-efficacy and the negative association between stigma and self-efficacy. The modified and extended Cha et al.’s model had a satisfactory fit. Interventions to improve mental health through mental health services, social support, and enhancement of adherence self-efficacy beliefs are required. |
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| Keywords: | Antiretroviral therapy adherence social support stigma China |
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