注射用棓丙酯致过敏性休克

1例60岁男性骨折患者为预防术后深静脉血栓,给予注射用棓丙酯180 mg+0.9%氯化钠注射液250 ml静脉滴注。约10 min后,患者突然出现胸闷、呼吸困难、面色苍白、口唇发绀、肢端发凉。心电监护示心率104次/min,血氧饱和度0.85,血压80/50 mm Hg(1 mm Hg=0.133 kPa)。立即停药并给予抗过敏、扩充血容量治疗及面罩给氧等处理。20 min后,患者过敏症状逐渐好转,血氧饱和度达0.96,血压升至100/58 mm Hg。

Anaphylactic shock induced by propylgallate for injection

A 60-year-old male with fracture received an IV infusion of propylgallate 180 mg in 0.9% sodium chloride 250 ml for prevention of deep vein thrombosis after undergoing surgery. About ten minutes later, the patient abruptly developed chest tightness, dyspnea, pallor, lip cyanosis, and cold peripheral extremities. ECG monitoring revealed a heart rate of 104 beats/min, his blood oxygen saturation was 0.85, and his blood pressure was 80/50 mm Hg. Propylgallate was discontinued immediately. Anti-allergic treatment, blood volume expansion, and mask oxygen were given. Twenty minutes later, his anaphylactie symptoms gradually improved, his blood oxygen saturation increased to 0.96, and his blood pressure increased to 100/58 mm Hg.