Cultivation of human tumors on the chorioallantoic membrane of the developing chick embryo

Summary Twenty-eight human tumors of various localization and structure were cultivated on chorioallantoic membrane of developing chick embryo. True growth of the tumors could not be obtained. Small parts of tumors survive for a short time and cause turbulent reaction in the chorioallantoic membrane. These pieces may be retransplanted, but later they are subjected to destruction and resolution. When normal human embryonic tissue was introduced — this only promoted a more prolonged preservation of the transplantate. However, it did not result in the true growth of transplanted tumors. Small pieces of papilloma of the urinary bladder appeared to be the most viable and withstood nine transplantations.Submitted by Active Member Acad. Med. Sci. USSR L.A. Zil'ber