中山市723例矮小症的病因分析

目的探讨身材矮小儿童的病因。方法回顾性总结矮小儿童共723例，男433例（59．89％），女290（40．11％）例，年龄2～19岁，平均年龄8．36岁，对其进行全面的病史采集和体格检查及相关实验室检查、影像学检查。结果引起矮小症的病因达19种，分别为：生长激素缺乏症（GHD）280例（38．7％）；生长激素神经分泌障碍（GHND）129例（17．8％）；病因分布比例在5％～10％的是特发性矮小、小于胎龄儿、甲状腺功能减低症、家族性矮小；性早熟、体质性青春发育延迟、Turner综合征、精神心理性身材矮小、锌缺乏症、地中海贫血所占比例在1％～5％；其余病因在723例患儿中所占比例小于1％。结论矮小症病因复杂，其中生长激素缺乏症是最常见疾病，对矮小症的发病因素需进一步的研究。

Etiologic analysis of 723 children with short stature in Zhongshan city

Objective To explore the etiologic investigation of 723 children with short stature.Methods Retrospective study of 723 cases of short stature,Among them 433 were males(59.89%),290 were females(40.11%),the average age was 8.36 years.All of the children were collected detail medical history and taken both physical and laboratory examination.Results There are 19 kinds of pathogeny that causes short stature.280(38.7%)cases were growth hormone deficiency(GHD).129(17.8%) cases were disorders of growth hormone neu...