Barrett食管的临床及病理研究

目的:探讨Barrett食管的临床及病理特点。方法:回顾性分析32例经胃镜及病理确诊的Barrett食管的临床表现、内镜及病理特点。结果:32例Barrett食管患者中临床出现反酸25例(78.1%)、胸骨后疼痛22例(68.8%)、烧心感18例(56.3%),无症状者6例(18.8%),胃镜检查伴有反流性食管炎表现者27例(84.4%),胆汁反流者10例(31.3%),病理检查结果全部病例食管下段均有柱状上皮化生。结论:Barrett食管多见于老年人,是反流性食管炎发展的结果,具有恶变为食管癌的潜在危险,其确诊须组织病理检查,内科治疗只能缓解及改善症状,发现恶变及早手术。

Clinical and pathological analysis of Barrett's esophagus

Objective To explore the clinical and pathological characteristic of Barrett's esophagus.Methods The clinical and pathological data of 32 cases of Barrett's esophagus proved by gastroscope and pathology were reviewed.Results The symptoms of reflux esophagitis included acid regurgitation in 25 cases(78.1%),pain posterior to breastbone in 22 cases(68.8%),pyrosis in 18 cases(56.3%),and non-symptom in 6 cases(18.8%).Reflux esophagitis occurred in 27 cases(84.4%),bile regurgitation in 10 cases(31.3%).Stratified squamous epithelium was replaced by columnar epithelium in low segment of esophagus proved by pathology.Conclusion Barrett's esophagus mainly occurs in the elders,and it is a result of gastroesophageal reflux.