| HPLC法测定双黄消炎片中盐酸小檗碱的含量 |
| |
| 引用本文： | 李伯军,梁帅,赵磊,刘丽,付艳敏,李冬梅.HPLC法测定双黄消炎片中盐酸小檗碱的含量[J].中国药师,2009,12(2). |
| |
| 作者姓名： | 李伯军 梁帅 赵磊 刘丽 付艳敏 李冬梅 |
| |
| 作者单位： | 1. 四平市药品检验所,吉林四平,136000
2. 吉林省四平市卫生学校 |
| |
| 摘 要： | 目的:建立双黄消炎片中盐酸小檗碱的含量测定HPLC方法;方法:Diomansil C_(18)柱(250mm×4.6mm,5μm),乙腈: 0.1%磷酸溶液(50:50)(每100 ml加十二烷基磺酸钠0.1g)为流动相,检测波长265nm;流速1.0ml·min~(-1)。结果:线性范围1.0～76.6μg·ml~(-1)(r=0.999 9)线性关系良好,平均回收率为102.4%,RSD为1.0%(n=6)。结论:方法简便快捷,可用于双黄消炎片的质量控制。
|
| 关 键 词： | 双黄消炎片 高效液相色谱 盐酸小檗碱 |
Determination the Content of Berberine Hydrochloride in Shuanghuangxiaoyan Tablets by HPLC |
| |
| Li Bojun,Liang Shuai,Zhao Lei,Liu Li,Fu Yanmin,Li Dongmei.Determination the Content of Berberine Hydrochloride in Shuanghuangxiaoyan Tablets by HPLC[J].China Pharmacist,2009,12(2). |
| |
| Authors: | Li Bojun Liang Shuai Zhao Lei Liu Li Fu Yanmin Li Dongmei |
| |
| Institution: | 2(Siping Institute for Drug Control; Jilin; Siping 136000; China; 2.Siping Health School); |
| |
| Abstract: | Objective:To establish an HPLC method for determination the content of berberine hydrochloride in Shuanghuangxiaoyan tablets.Method:The Diamonsil C_(18) column(250mm×4.6mm,5μm) was used,the mobile phase was acetonitrile -0.1%phosphoric acid solution(50:50),the flow rate was 1.0ml·min~(-1),the detection wavelength was 265nm.Result:The standard curve of berberine hydrochloride was linear in the rang of 1.0-76.6μg·ml~(-1)(r=0.999 9),the average recovery was 102.4%with RSD 1.0%(n=6).Conclusion:The method is sim... |
| |
| Keywords: | Shuanghuangxiaoyan tablets HPLC Berberine hydrochloride |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国药师》浏览原始摘要信息 |
| 点击此处可从《中国药师》下载免费的PDF全文 |
|
