|
|||||
|
|
| 国产与进口重组人粒细胞巨噬细胞集落刺激因子药物经济学评价比较 | |
| 引用本文： | 胡善联,沈志祥,袁弥满,曾晓颖. 国产与进口重组人粒细胞巨噬细胞集落刺激因子药物经济学评价比较[J]. 中国新药与临床杂志, 2000, 19(4): 309-312 |
| 作者姓名： | 胡善联 沈志祥 袁弥满 曾晓颖 |
| 作者单位： | 1. 上海医科大学,卫生经济学教研室,上海,200032 2. 上海第二医科大学,附属瑞金医院,血液科,上海,200025 3. 上海医科大学,附属中山医院,血液科,上海,200032 |
| 摘 要： | 采用前瞻性及自身交叉对照 2种调查设计方法对国产及进口重组人粒细胞巨噬细胞集落刺激因子 (rHuGM CSF)进行了血液肿瘤病人化疗后升白细胞的临床疗效及药物经济学评价。结果证明 2组临床疗效即升白细胞效果无显著性差异。最小成本法比较 ,如果应用国产品其期望有效治疗成本平均每例可节省人民币 70 0 0～ 2 0 0 0 0元。 |
| 关 键 词： | 粒细胞巨噬细胞集落刺激因子 白血病 药学经济学 |
Pharmacoeconomic study on domestic and imported rHuGM-CSF product |
|
| HU Shan-Lian,SHEN Zhi-Xiang,YUAN Mi-Man,ZEN Xiao-Ying. Pharmacoeconomic study on domestic and imported rHuGM-CSF product[J]. Chinese Journal of New Drugs and Clinical Remedies, 2000, 19(4): 309-312 | |
| Authors: | HU Shan-Lian SHEN Zhi-Xiang YUAN Mi-Man ZEN Xiao-Ying |
| Abstract: | A prospective and a selfcross control clinical trial and pharmacoeconomic study were conducted respectively in two groups of hematologic malignancies patients by using domestic rHuGMCSF product (Topleucon) and imported one (Leucomax). The results showed that there were no significant difference in both clinical efficacy and raising the amount of leucocytes in the two groups. The minimum cost analysis illustrated that the expected cost of 100 % effective treatment per patient in Topleucon group is 7, 000～20,000 yuan (RMB) less than that in Leucomax group. |
| Keywords: | granulocyte-macrophage coloy-stimulating factor leukemia pharmaceutical economics |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |