| 乌灵菌粉化学成分研究 |
| |
| 引用本文： | 陆静娴,罗镭,陈勇,陈建,祝明.乌灵菌粉化学成分研究[J].中国现代应用药学,2014,31(5):541-543. |
| |
| 作者姓名： | 陆静娴 罗镭 陈勇 陈建 祝明 |
| |
| 作者单位： | 浙江省食品药品检验研究院，杭州 310004;浙江省食品药品检验研究院，杭州 310004;浙江省食品药品检验研究院，杭州 310004;浙江佐力药业股份有限公司，浙江 湖州 313299;浙江省食品药品检验研究院，杭州 310004 |
| |
| 基金项目： | “重大新药创制”国家科技重大专项(2012ZX09304005) |
| |
| 摘 要： | 目的 对乌灵菌粉的化学成分进行研究。方法 采用硅胶柱层析、制备液相等多种分离手段，对乌灵菌粉中石油醚、乙酸乙酯部分进行提取、分离、纯化，通过核磁数据进行结构鉴定。结果 分离并鉴定4个化合物，分别为: 5-hydroxymellein(1)、5-carboxylmellein(2)、金雀异黄素(3)和5-methylmellein(4)。结论 化合物2，3，4为首次从乌灵菌粉提取分离得到；化合物1，2，4为乌灵菌粉的特征性成分。
|
| 关 键 词： | 乌灵菌粉 化学成分 |
| 收稿时间： | 2013/3/28 0:00:00 |
| 修稿时间： | 2/9/2014 12:00:00 AM |
Chemical Constituents of Wuling Fermentative Powder |
| |
| LU Jingxian,LUO Lei,CHEN Yong,CHEN Jian and ZHU Ming.Chemical Constituents of Wuling Fermentative Powder[J].The Chinese Journal of Modern Applied Pharmacy,2014,31(5):541-543. |
| |
| Authors: | LU Jingxian LUO Lei CHEN Yong CHEN Jian and ZHU Ming |
| |
| Institution: | Zhejiang Institute for Food and Drug Control, Hangzhou 310004, China;Zhejiang Institute for Food and Drug Control, Hangzhou 310004, China;Zhejiang Institute for Food and Drug Control, Hangzhou 310004, China;Zhejiang Jolly Pharmaceutical Co. Ltd., Huzhou 313299, China;Zhejiang Institute for Food and Drug Control, Hangzhou 310004, China |
| |
| Abstract: | OBJECTIVE To study the chemical constituents of Wuling fermentative powder. METHODS Four components were extracted, separated and purified from the parts of petroleum and acetic ether by the means of silica gel column chromatography and preparative HPLC methods, and identified by NMR data. RESULTS The four compounds were elucidated as: 5-hydroxymellein(1), 5-carboxylmellein(2), genistein(3) and 5-methylmellein(4). CONCLUSION The later three components are obtained for the first time from Wuling Fermentative powder. 1, 2 and 4 are the characteristic components in Wuling Fermentative powder. |
| |
| Keywords: | Wuling fermentative powder chemical constituents |
|
| 点击此处可从《中国现代应用药学》浏览原始摘要信息 |
| 点击此处可从《中国现代应用药学》下载免费的PDF全文 |
|
