| 复方甘草酸苷联合川芎嗪治疗酒精性肝病的疗效观察 |
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| 引用本文： | 韩俊岭,韩〓莹,张春艳,李朝晖,曲磊红,李〓莉,郑〓岳. 复方甘草酸苷联合川芎嗪治疗酒精性肝病的疗效观察[J]. 南京医科大学学报(自然科学版), 2009, 29(11): 1607-1610 |
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| 作者姓名： | 韩俊岭 韩〓莹 张春艳 李朝晖 曲磊红 李〓莉 郑〓岳 |
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| 作者单位： | 秦皇岛市第一医院消化内科,河北,秦皇岛,066002;秦皇岛港口医院检验科,河北,秦皇岛,066002 |
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| 摘 要： | 目的:观察复方甘草酸苷联合川芎嗪治疗酒精性肝病的疗效?方法:将160例酒精性肝病患者随机分为对照组?复方甘草酸苷组?川芎嗪组及联合治疗组,治疗4周后观察肝功能?肝纤维化指标?转化生长因子β1(TGFβ1)?白细胞介素-6(IL-6)?瘦素(Leptin)及肿瘤坏死因子-α(TNF-α)?结果:各组治疗后肝功能较治疗前均显著好转,肝纤维化指标?TGFβ1?IL-6?Leptin及TNF-α较治疗前均显著下降(P < 0.05),对照组?复方甘草酸苷组及川芎嗪组之间治疗后肝功能?肝纤维化指标?TGFβ1?IL-6?Leptin及TNF-α无显著性差异(P > 0.05),联合治疗组治疗后肝功能较对照组?复方甘草酸苷组及川芎嗪组显著改善(P < 0.05),肝纤维化指标?TGFβ1?IL-6?Leptin及TNF-α较对照组?复方甘草酸苷组及川芎嗪组显著下降(P < 0.05)?结论:复方甘草酸苷联合川芎嗪治疗酒精性肝病有效?
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| 关 键 词： | 复方甘草酸苷 川芎嗪 酒精性肝病 疗效 |
| 收稿时间： | 2009-05-05 |
Observation of curative effects of compound glycyrrhizin combined with ligustrazine on patients with alcoholic liver disease |
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| HAN Jun-ling,HAN Ying,ZHANG Chun-yan,LI Zhao-hui,QU Lei-hong,LI Li and ZHENG Yue. Observation of curative effects of compound glycyrrhizin combined with ligustrazine on patients with alcoholic liver disease[J]. Acta Universitatis Medicinalis Nanjing, 2009, 29(11): 1607-1610 |
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| Authors: | HAN Jun-ling HAN Ying ZHANG Chun-yan LI Zhao-hui QU Lei-hong LI Li ZHENG Yue |
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| Affiliation: | Department of Gastroenterology, the First Hospital of Qinhuangdao,Qinhuangdao 066002;Department of Clinical Laboratory,Qinhuangdao Harbour Hospital,Qinhuangdao 066002,China;Department of Gastroenterology, the First Hospital of Qinhuangdao,Qinhuangdao 066002;Department of Gastroenterology, the First Hospital of Qinhuangdao,Qinhuangdao 066002;Department of Gastroenterology, the First Hospital of Qinhuangdao,Qinhuangdao 066002;Department of Gastroenterology, the First Hospital of Qinhuangdao,Qinhuangdao 066002;Department of Gastroenterology, the First Hospital of Qinhuangdao,Qinhuangdao 066002 |
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| Abstract: | |
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| Keywords: | compound glycyrrhizin ligustrazine alcoholic liver disease curative effect |
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