系统性硬化合并腹膜后纤维化1例

系统性硬化（SSc）又称为硬皮病、进行性系统性硬化，它是一种原因不明的，以小血管功能结构异常为主的，皮肤、内脏纤维化出现皮肤变硬和增厚，免疫系统活化和自身免疫为特征的全身性疾病，女性多见，多数发病年龄在30～50岁。根据患者皮肤受累的情况将SSc分为局限性皮肤性系统性硬化、CREST综合症、弥漫性皮肤性系统性硬化、无皮肤硬化的系统性硬化及重叠综合征，多合并心、肺、肾的病变，故预后不良。

Systemic sclerosis a merger retroperitoneal fibrosis

systemic sclerosis also known as scleroderma, progressive systemic sclerosis, it is a reason unknown to small blood vessel function structure is abnormal, the skin, the visceral fibrosis occurrence skin harden and thickening, the immune system activation and autoimmune disease characterized by systemic, women see more, most of the onset age in the 30-50 years old. According to patients with skin involvement of SSc will be divided into limitations skin sex systemic sclerosis, CREST, and diffuse skin sex systemic sclerosis, no skin hardening of the systemic sclerosis and overlap syndrome, merge cardiopulmonary renal lesions, so poor prognosis.