Isoniazid overdose treated with high-dose pyridoxine |
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Authors: | B E Yarbrough J P Wood |
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Affiliation: | Department of Internal Medicine, Division of General Medicine, Medical College of Virginia, Richmond, Virginia, USA |
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Abstract: | Large doses of pyridoxine recently have been shown to prevent the seizures and acidosis caused by ingestion of more than two to three grams of isoniazid. We present three cases of massive isoniazid ingestion, producing seizures and acidosis, that were treated successfully by administration of one gram of pyridoxine intravenously for each gram of isoniazid ingested. |
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Keywords: | drug overdose, isoniazid isoniazid, overdose overdose, isoniazid, treated with pyridoxine pyridoxine, for isoniazid overdose |
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