302例患过天花者HBV血清学调查研究

对302例患过天花者这一特殊人群进行了HBV血清学调查,结果HBsAg阳性率(1.3%)分别显著低于对照组1(8.3%)和对照组2(8.6%)(P<0.001)。两对照组HBsAg阳性率无显著性差异(P>0.05)。患过天花者HBV感染率(19.2%)也分别显著低于对照组1(47.7%)和对照组2(51.3%)(P<0.001)。对上述三组细胞免疫功能测定结果,病例组玫瑰花结形成率及淋巴细胞转化率均分别显著高于两对照组。故认为上述结果是患过天花者细胞免疫功能增强,干扰乙型肝炎病毒感染所致。

Serologic Investigation of HBV in 302 Patients who had a History of Smallpox

This paper provides serologic investigation of HBV in 302 persons who had a history of smallpox in Zhumadian County. The results showed that the HBsAg positivity rate (1.3%) was significantly lower than those of the control group 1 (8.3%) and 2 (8.6%) (P less than 0.001). The HBsAg positivity rate between the two control groups had no significant difference (P greater than 0.05). The HBV infection rate (19.2%) was also lower than those of control group 1 (47.7%) and 2 (51.3%) (P less than 0.001). There was not much difference between the two control groups. The determination of cellular immunity showed that the rosette positivity rate (75.93%) and lymphocyte conversion rate (70.39%) of the patients' group were higher than those of control group 1 (62.3% and 52.9%) and 2 (60.93% and 55.3%). It may suggested that patients having had smallpox might have enhanced cellular immunity which might interfere with HBV infection.