| 创伤愈合中肥大细胞的形态变化及定量研究 |
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| 引用本文： | 高亚兵,崔彩彬,杨瑞彪,崔玉芳,王德文.创伤愈合中肥大细胞的形态变化及定量研究[J].中国体视学与图像分析,1997(3). |
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| 作者姓名： | 高亚兵 崔彩彬 杨瑞彪 崔玉芳 王德文 |
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| 作者单位： | 军事医学科学院放射医学研究所 |
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| 摘 要： | 创伤愈合过程中，参与或涉及的种类很多，其中肥大细胞、成纤维细胞等对创伤愈合起着极为重要的作用。本实验以雄性北京小型猪为创伤模型，观察了碱性成纤维细胞生长因子（ｂＦＧＦ）治疗后肥大细胞（Ｍａｓｔｃｅｌ，ＭＣ）在创伤愈合中的动态变化，并结合图像分析进行了定量研究。结果发现：创伤后ＭＣ数量和ＭＣ内颗粒数量发生了改变，ｂＦＧＦ也参与了创伤修复过程。本研究的结果提示ｂＦＧＦ和ＭＣ可能参与了这一过程，但对于这两者的关系和在其中的作用均需要进一步研究。
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| 关 键 词： | 创伤愈合 肥大细胞 bFGF（碱性成纤维细胞生长因子） |
Morphological changes and quantitative study of mast cells in wound healing |
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| Gao Yabing,Cui Caibin,Yang Ruibiao,Cui Yufang,Wang Dewen.Morphological changes and quantitative study of mast cells in wound healing[J].Chinese Journal of Stereology and Image Analysis,1997(3). |
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| Authors: | Gao Yabing Cui Caibin Yang Ruibiao Cui Yufang Wang Dewen |
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| Abstract: | Although various kinds of cells are involved in the process of wound healing, mast cell (MC) and fibroblast play a vital role in this event. Dynamic changes of mast cells were in the process of wound healing in small type of Beijing male pigs after wounding and treatment with basic fibroblast growth factor (bFGF). It was found that the number of mast cells and the quantity of granules in the mast cells showed marked changes, suggesting that bFGF and mast cell might involve in the wound healing process. |
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| Keywords: | wound healing mast cell fibroblast basic fibroblast growth factor |
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