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长春瑞滨联合顺铂治疗晚期非小细胞肺癌160例近期疗效
引用本文:劳逸,陈绍锋,王伟,许德明,蔡永广.长春瑞滨联合顺铂治疗晚期非小细胞肺癌160例近期疗效[J].肿瘤防治研究,2004,31(2):103-104.
作者姓名:劳逸  陈绍锋  王伟  许德明  蔡永广
作者单位:524002,广东湛江,广东省农垦中心医院
摘    要: 目的 观察长春瑞滨 (NVB)和顺铂 (DDP)联合治疗晚期非小细胞肺癌 (NSCLC)的临床疗效及毒副作用。方法  160例Ⅲb~Ⅳ期初次治疗的非小细胞肺癌 ,用NVB联合DDP(NP方案 )治疗 :NVB2 5mg/m2 ,静滴d1,8,DDP 80mg/m2 静滴d1。结果 有效率 (CR +PR) 55.6% ,中位缓解期 6.2个月。中位生存期 12 .2个月。主要毒副反应为骨髓抑制。结论 NP方案治疗晚期非小细胞肺癌疗效高 ,副反应少 ,病人可耐受 ,值得临床作为一线治疗推广

关 键 词:长春瑞滨  顺铂  非小细胞肺癌  化疗
文章编号:1000-8578(2004)02-0103-02
收稿时间:2003-1-27
修稿时间:2003-4-2

Vinorelbine Plus Cisplatin Combination Chemotherapy in Advanced Non-small-cell Lung Cancer
LAO Yi,CHEN Shao feng,WANG Wei,et al Central Hospital of GuangDong Province Agricultural Reclamarion,Zhanjiang ,China.Vinorelbine Plus Cisplatin Combination Chemotherapy in Advanced Non-small-cell Lung Cancer[J].Cancer Research on Prevention and Treatment,2004,31(2):103-104.
Authors:LAO Yi  CHEN Shao feng  WANG Wei  Central Hospital of GuangDong Province Agricultural Reclamarion  Zhanjiang  China
Institution:LAO Yi,CHEN Shao feng,WANG Wei,et al Central Hospital of GuangDong Province Agricultural Reclamarion,Zhanjiang 524002,China
Abstract:Objective To evaluate the efficacy and toxicity of vinorelbine(NVB) plus cisplatin(NP regimen) combination chemotherapy in advanced non small cell lung cancer(NSCLC).Methods A total of 160 patients with advanced non small cell lung cancer were treated by NP regimen: NVB 25 mg/m 2,d 1,8 ; cisplatin 80 mg/m 2,d 1. All of them had stage Ⅲ b~Ⅳ disease, They were primary treatment. Results The overall response rate (RR) was 55.6% ,The median response time 6.2 months. The median survival tim...
Keywords:Vinorelbine  Cisplatin  Non  small  cell lung cancer  Chemotherapy
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