CT/MRI图像融合技术在颅底肿瘤检查中的应用价值

目的：探讨CT/MRI图像融合（image fusion）技术在颅底肿瘤检查中的应用价值。方法：搜集经MRI检出并均行高分辨率CT扫描的颅底肿瘤患者33例,将同一患者的CT、MRI图像融合。两名高年资放射科医师共同协商评价CT/MRI融合图像、MRI图像,评价的内容包括病变内部的密度或信号、病变的轮廓、病变与邻近血管的关系、病变与周围神经的关系、病变邻近骨质的破坏或硬化情况、病变周围软组织的改变,依据两种图像所能显示的病变信息等级评分,采用配对t检验分析比较的结果。结果：与单独MRI图像相比,CT/MRI融合图像在显示病变内部结构及其与周围血管、神经的关系方面无明显优势（P〉0.05）;而在病变的轮廓、邻近骨质的改变情况方面明显优于单独MRI图像（P〈0.05,P〈0.01）。结论：CT/MRI融合图像显示病变的综合信息明显优于单独的MRI图像,能够直观地为临床提供更加全面的信息。

Value of CT/MRI Image Fusion in the Examination of Skull Base Neoplasms:a Preliminary Study

Objective： To investigate the value of CT/MRI image fusion in the examination of skull base neoplasms. Methods：Thirty-three patients with skull base tumors underwent MRI examination and carried out HRCT scan in three days. CT and MRI images of same patient were fused accurately. Two senior radiologists compared and evaluated the MRI images and fused images by consultation which included the density or signal of the tumor, tumor delineation, the relations between the tumor and adjacent blood vessels, nerves, bones and soft tissues. The displayed ability of MRI images and fused images were evaluated separately according to a three-step scoring system. The results were compared using a paired student＇s t test. Results：The diagnostic concordance of the MRI and fusion images by two radiologists was good. The fusion images were not superior to the MRI images in the display of the density or signal of the tumor and relationship between tumor and adjacent vessels and nerves （P〉0.05）. But were much better in the presentation of the tumor contour and skeleton than the MRI images alone （P〈0.05, P〈0.01）. Conclusion： More plentiful and visible images could be provided by CT/MRI image fusion for physicians and surgeons,so it is helpful to further diagnosis and treatment of such patients.