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血管内皮生长因子(VEGF)在食管癌中的表达及临床意义
引用本文:崔玉霞,李淼晶. 血管内皮生长因子(VEGF)在食管癌中的表达及临床意义[J]. 牡丹江医学院学报, 2007, 28(6): 28-29
作者姓名:崔玉霞  李淼晶
作者单位:1. 哈尔滨医科大学大庆校区,黑龙江,大庆,163319
2. 牡丹江医学院,黑龙江,牡丹江,157011
摘    要:目的:探讨VEGF在食管癌中的表达及与肿瘤组织的分化、有无淋巴结转移及肿瘤浸润的关系。方法:收集44例原发性食管癌,20例癌旁组织和20例正常组织,采用免疫组化(SP)方法检测VEGF的表达。结果:VEGF表达在食管癌组织中明显高于其他组织,且与其病理分级、有无淋巴结转移及肿瘤浸润有相关性,P〈0.05。结论:VEGF与食管癌病变进展有关,可作为食管癌预后判断的客观指标。

关 键 词:食管癌  VEGF  免疫组化
修稿时间:2007-06-19

EXPRESSION OF VEGF IN ESOPHAGEAL CARCINOMA AND ITS CLINICAL SIGNIFICANCE
Cui yuxia. EXPRESSION OF VEGF IN ESOPHAGEAL CARCINOMA AND ITS CLINICAL SIGNIFICANCE[J]. Journal of Mudanjiang Medical College, 2007, 28(6): 28-29
Authors:Cui yuxia
Affiliation:Cui yuxia et al (Daqing School, Harbin Medical University Heilongjiang Daqing 163319)
Abstract:Objective:To investigate expression of VEGF in esophageal carcinoma and its clinical significance. Methods:Immunohis -tochemical staining S-Pmethod was used to detect VEGF expression in normal mucous tissue (20 cases), in the tissue adjacent to tumor (20cases) and in esophageal carcinoma tissue (44cases). level in esophageal carcinoma tissue was much higher than those in normal mucous tissue and in the tissue adjacent to tumor. There was significant difference between the three teams( P 〈 0.05 ). Conelusion:VEGF is associated with the growth of esophageal carcinoma. VEGF could be considered as an objective predictable index for prognosis of esophageal carcinoma.
Keywords:VEGF
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